Skip header and navigation
The BC Cancer Library

Delivering timely service and evidence-informed resources to people in BC and the Yukon facing cancer and those involved in oncology care or research.

  Refine by:

Refine by:

Format

20 records – page 1 of 1.

NCCN guidelines for patients : acute myeloid leukemia

https://bccalibrary.andornot.com/en/permalink/catalog124877
National Comprehensive Cancer Network (NCCN). Plymouth Meeting, PA: National Comprehensive Cancer Network , 2023.
Audience
Patient or Public
Call Number
WH265 N277am 2023
Availability
4 copies, 4 available
More Information
  2 read online  
Alternate Title
National Comprehensive Cancer Network guidelines for patients : acute myeloid leukemia
Corporate Author
National Comprehensive Cancer Network (NCCN)
Place of Publication
Plymouth Meeting, PA
Publisher
National Comprehensive Cancer Network
Publication Date
2023
Physical Description
80 p. : col. ill. ; 29 cm
Series
NCCN guidelines for patients
Subjects
Popular Work
Leukemia, Myeloid, Acute
ISBN
9781954190887
Language
English
Material Type
Book
Online
Audience
Patient or Public
Location
Internet
Abbotsford Cancer Info Ctr
Kelowna Cancer Info Ctr
Victoria Cancer Info Ctr
Vancouver Library
Call Number
WH265 N277am 2023
Read Online
https://www.nccn.org/patients/guidelines/content/PDF/aml-patient.pdf
https://www.nccn.org/patientresources/patient-resources/guidelines-for-patients

Copies

c.1 BC Cancer Agency KEL Cancer Info Ctr Available
c.1 BC Cancer Agency VIC Cancer Info Ctr Available
c.1 BC Cancer Agency VAN Library Available
c.1 BC Cancer Agency ARHCC Cancer Info Ctr Available
Show Less

Somatic mutations in human cancer : emerging patterns from sequencing the protein kinase gene family

https://bccalibrary.andornot.com/en/permalink/catalog15578
Futreal, Andy. [Vancouver, BC?]: BC Cancer Agency. Multi-Media Services , 2007.
Audience
Professional
Call Number
QZ206 B365 2007 v.218
Availability
1 copy, 1 available
More Information
Alternate Title
Monday noon seminar series
Author
Futreal, Andy
Corporate Author
BC Cancer Research Centre Seminar Series
Place of Publication
[Vancouver, BC?]
Publisher
BC Cancer Agency. Multi-Media Services
Publication Date
2007
Physical Description
60 minutes
Series
BC Cancer Research Centre seminar series 218
Subjects
Neoplasms - genetics - DVD
Protein Kinases - DVD
Mutation - genetics - DVD
Language
English
Material Type
Video
DVD
Audience
Professional
Location
Vancouver Library AV Room
Call Number
QZ206 B365 2007 v.218

Copies

c.1 BC Cancer Agency VAN Library AV Room Available
Show Less

Bioenergetic blackout. How do cells respond to metabolic crisis?

https://bccalibrary.andornot.com/en/permalink/catalog16384
Lum, Julian J. [Vancouver, BC?]: BC Cancer Agency. Multi-Media Services , 2008.
Audience
Professional
Call Number
QZ206 B365 2008 v.248
Availability
1 copy, 1 available
More Information
Alternate Title
Monday noon seminar series
Author
Lum, Julian J
Corporate Author
BC Cancer Research Centre Seminar Series
Place of Publication
[Vancouver, BC?]
Publisher
BC Cancer Agency. Multi-Media Services
Publication Date
2008
Physical Description
60 minutes
Series
BC Cancer Research Centre seminar series 248
Subjects
Energy Metabolism - genetics
Cell Proliferation
Neoplasms - metabolism
Language
English
Material Type
Video
DVD
Audience
Professional
Location
Vancouver Library AV Room
Call Number
QZ206 B365 2008 v.248

Copies

c.1 BC Cancer Agency VAN Library AV Room Available
Show Less

Leukemia stem cells in AML

https://bccalibrary.andornot.com/en/permalink/catalog16105
Buske, Christian. [Vancouver, BC?]: BC Cancer Agency. Multi-Media Services , 2007.
Audience
Professional
Call Number
QZ206 B365 2007 v.238
Availability
1 copy, 1 available
More Information
Alternate Title
Monday noon seminar series
Author
Buske, Christian
Corporate Author
BC Cancer Research Centre Seminar Series
Place of Publication
[Vancouver, BC?]
Publisher
BC Cancer Agency. Multi-Media Services
Publication Date
2007
Physical Description
60 minutes
Series
BC Cancer Research Centre seminar series 238
Subjects
Leukemia
Leukemia, Myeloid, Acute
Neoplastic Stem Cells
Language
English
Material Type
Video
DVD
Audience
Professional
Location
Vancouver Library AV Room
Call Number
QZ206 B365 2007 v.238

Copies

c.1 BC Cancer Agency VAN Library AV Room Available
Show Less

Identification of a novel oncogene in uveal melanoma

https://bccalibrary.andornot.com/en/permalink/catalog17851
Van Raamsdonk, Catherine. [Vancouver, BC?]: BC Cancer Agency. Multi-Media Services , 2009.
Audience
Professional
Call Number
QZ206 B365 2009 v.263
Availability
1 copy, 1 available
More Information
Alternate Title
Monday noon seminar series
Author
Van Raamsdonk, Catherine
Corporate Author
BC Cancer Research Centre Seminar Series
Place of Publication
[Vancouver, BC?]
Publisher
BC Cancer Agency. Multi-Media Services
Publication Date
2009
Physical Description
60 minutes
Series
BC Cancer Research Centre seminar series 263
Subjects
Oncogenes
Uveal Neoplasms - genetics
Melanoma
Language
English
Material Type
Video
DVD
Audience
Professional
Location
Vancouver Library AV Room
Call Number
QZ206 B365 2009 v.263

Copies

c.1 BC Cancer Agency VAN Library AV Room Available
Show Less

Dead-end of testicular cancer

https://bccalibrary.andornot.com/en/permalink/catalog15962
Nadeau, Joseph. [Vancouver, BC?]: BC Cancer Agency. Multi-Media Services , 2007.
Audience
Professional
Call Number
QZ206 B365 2007 v.233
Availability
1 copy, 1 available
More Information
Alternate Title
Monday noon seminar series
Author
Nadeau, Joseph
Corporate Author
BC Cancer Research Centre Seminar Series
Place of Publication
[Vancouver, BC?]
Publisher
BC Cancer Agency. Multi-Media Services
Publication Date
2007
Physical Description
60 minutes
Series
BC Cancer Research Centre seminar series 233
Subjects
Testicular Neoplasms - genetics
Testicular Neoplasms - etiology
Carcinogens, Environmental
Germ Cells - metabolism
Mutation - genetics
Neoplasm Proteins
Gene Expression Regulation
Epigenesis, Genetic
Language
English
Material Type
Video
DVD
Audience
Professional
Location
Vancouver Library AV Room
Call Number
QZ206 B365 2007 v.233

Copies

c.1 BC Cancer Agency VAN Library AV Room Available
Show Less

Tumor type-specific effects of oncomir-1 : lessons from mouse models and cancer genomics

https://bccalibrary.andornot.com/en/permalink/catalog21207
Thomas-Tikhonenko, Andrei. [Vancouver, BC?]: BC Cancer Agency. Multi-Media Services , 2013.
Audience
Professional
Call Number
QZ206 B365 2013 v.337
Availability
1 copy, 1 available
More Information
Alternate Title
Monday noon seminar series
BCCA Research Seminar Series
Author
Thomas-Tikhonenko, Andrei
Corporate Author
BC Cancer Research Centre Seminar Series
Place of Publication
[Vancouver, BC?]
Publisher
BC Cancer Agency. Multi-Media Services
Publication Date
2013
Physical Description
60 minutes
Series
BC Cancer Research Centre seminar series 337
Subjects
MicroRNAs - genetics
Genes, Neoplasm
Disease Models, Animal
Oncogenes
Gene Expression Profiling
Language
English
Material Type
Video
DVD
Audience
Professional
Location
Vancouver Library AV Room
Call Number
QZ206 B365 2013 v.337

Copies

c.1 BC Cancer Agency VAN Library AV Room Available
Show Less

Metabolic regulation by the AMP-activated protein kinase (AMPK) : implications for cancer biology

https://bccalibrary.andornot.com/en/permalink/catalog20184
Jones, Russell G. [Vancouver, BC?]: BC Cancer Agency. Multi-Media Services , 2011.
Audience
Professional
Call Number
QZ206 B365 2011 v.307
Availability
1 copy, 1 available
More Information
Alternate Title
Monday noon seminar series
BCCA Research Seminar Series
Author
Jones, Russell G
Corporate Author
BC Cancer Research Centre Seminar Series
Place of Publication
[Vancouver, BC?]
Publisher
BC Cancer Agency. Multi-Media Services
Publication Date
2011
Physical Description
60 minutes
Series
BC Cancer Research Centre seminar series 307
Subjects
AMP-Activated Protein Kinases
Cell Transformation, Neoplastic
Neoplasms - metabolism
Molecular Biology
Language
English
Material Type
Video
DVD
Audience
Professional
Location
Vancouver Library AV Room
Call Number
QZ206 B365 2011 v.307

Copies

c.1 BC Cancer Agency VAN Library AV Room Available
Show Less

PI 3-kinase and cancer metabolism

https://bccalibrary.andornot.com/en/permalink/catalog20641
Cantley, Lewis. [Vancouver, BC?]: BC Cancer Agency. Multi-Media Services , 2012.
Audience
Professional
Call Number
QZ206 B365 2012 v.316
Availability
1 copy, 1 available
More Information
Alternate Title
Richard T. Israel's QC memorial lecture
Author
Cantley, Lewis
Corporate Author
BC Cancer Research Centre Seminar Series
Place of Publication
[Vancouver, BC?]
Publisher
BC Cancer Agency. Multi-Media Services
Publication Date
2012
Physical Description
60 minutes
Series
BC Cancer Research Centre seminar series 316
Subjects
Neoplasms - metabolism
Protein Isoforms - metabolism
Phosphatidylinositol 3-Kinases
Adaptor Proteins, Signal Transducing
Language
English
Material Type
Video
DVD
Audience
Professional
Location
Vancouver Library AV Room
Call Number
QZ206 B365 2012 v.316

Copies

c.1 BC Cancer Agency VAN Library AV Room Available
Show Less

Structural, sequence, and functional analysis of tumor genomes using end sequence profiling

https://bccalibrary.andornot.com/en/permalink/catalog15577
Collins, Colin. [Vancouver, BC?]: BC Cancer Agency. Multi-Media Services , 2007.
Audience
Professional
Call Number
QZ206 B365 2007 v.217
Availability
1 copy, 1 available
More Information
Alternate Title
Monday noon seminar series
Author
Collins, Colin
Corporate Author
BC Cancer Research Centre Seminar Series
Place of Publication
[Vancouver, BC?]
Publisher
BC Cancer Agency. Multi-Media Services
Publication Date
2007
Physical Description
60 minutes
Series
BC Cancer Research Centre seminar series 217
Subjects
Gene Expression Profiling - DVD
Neoplasms - genetics - DVD
Oncogenes - DVD
Language
English
Material Type
Video
DVD
Audience
Professional
Location
Vancouver Library AV Room
Call Number
QZ206 B365 2007 v.217

Copies

c.1 BC Cancer Agency VAN Library AV Room Available
Show Less

Characterization and targeting of leukemia stem cells

https://bccalibrary.andornot.com/en/permalink/catalog16104
Jordan, Craig T. [Vancouver, BC?]: BC Cancer Agency. Multi-Media Services , 2007.
Audience
Professional
Call Number
QZ206 B365 2007 v.237
Availability
1 copy, 1 available
More Information
Alternate Title
Monday noon seminar series
Author
Jordan, Craig T
Corporate Author
BC Cancer Research Centre Seminar Series
Place of Publication
[Vancouver, BC?]
Publisher
BC Cancer Agency. Multi-Media Services
Publication Date
2007
Physical Description
60 minutes
Series
BC Cancer Research Centre seminar series 237
Subjects
Leukemia
Neoplastic Stem Cells
Proto-Oncogene Proteins
Language
English
Material Type
Video
DVD
Audience
Professional
Location
Vancouver Library AV Room
Call Number
QZ206 B365 2007 v.237

Copies

c.1 BC Cancer Agency VAN Library AV Room Available
Show Less

Linking cancer endocrinology to cancer metabolism

https://bccalibrary.andornot.com/en/permalink/catalog20875
Pollak, Michael. [Vancouver, BC?]: BC Cancer Agency. Multi-Media Services , 2013.
Audience
Professional
Call Number
QZ206 B365 2013 v.325
Availability
1 copy, 1 available
More Information
Alternate Title
Monday noon seminar series
BCCA Research Seminar Series
Author
Pollak, Michael
Corporate Author
BC Cancer Research Centre Seminar Series
Place of Publication
[Vancouver, BC?]
Publisher
BC Cancer Agency. Multi-Media Services
Publication Date
2013
Physical Description
60 minutes
Series
BC Cancer Research Centre seminar series 325
Subjects
Endocrine System
Hormones
Neoplasms - metabolism
Insulin-Like Growth Factor Binding Proteins
Language
English
Material Type
Video
DVD
Audience
Professional
Location
Vancouver Library AV Room
Call Number
QZ206 B365 2013 v.325

Copies

c.1 BC Cancer Agency VAN Library AV Room Available
Show Less

Cancer cell metabolism : basic principles and opportunities for translation

https://bccalibrary.andornot.com/en/permalink/catalog21145
DeBerardinis, Ralph J. [Vancouver, BC?]: BC Cancer Agency. Multi-Media Services , 2013.
Audience
Professional
Call Number
QZ206 B365 2013 v.333
Availability
1 copy, 1 available
More Information
Alternate Title
Monday noon seminar series
BCCA Research Seminar Series
Author
DeBerardinis, Ralph J
Corporate Author
BC Cancer Research Centre Seminar Series
Place of Publication
[Vancouver, BC?]
Publisher
BC Cancer Agency. Multi-Media Services
Publication Date
2013
Physical Description
60 minutes
Series
BC Cancer Research Centre seminar series 333
Subjects
Cell Transformation, Neoplastic - metabolism
Translational Medical Research
Cell Differentiation
Glucose Oxidase
Language
English
Material Type
Video
DVD
Audience
Professional
Location
Vancouver Library AV Room
Call Number
QZ206 B365 2013 v.333

Copies

c.1 BC Cancer Agency VAN Library AV Room Available
Show Less

Surviving triple negative breast cancer : hope, treatment, and recovery

https://bccalibrary.andornot.com/en/permalink/catalog21249
Prijatel, Patricia. New York, NY: Oxford University Press , 2013.
Audience
Patient or Public
Call Number
WP870 P951 2013
Availability
6 copies, 5 available
More Information
  1 read online  
Author
Prijatel, Patricia
Place of Publication
New York, NY
Publisher
Oxford University Press
Publication Date
2013
Physical Description
xvii, 223 p. : ill. ; 25 cm.
Series
Proquest Ebook Central
ebrary books for public
Subjects
Triple Negative Breast Neoplasms
Breast Neoplasms - therapy
Breast Neoplasms - genetics
Breast Neoplasms - metabolism
Receptors, Estrogen - genetics
Receptors, Progesterone - genetics
Personal Narratives
Popular Work
ISBN
9780195387629
9780199908738
9780199393855
Language
English
Material Type
Book
Ebook
Audience
Patient or Public
Location
Vancouver Library
Kelowna Cancer Info Ctr
Victoria Cancer Info Ctr
Abbotsford Cancer Info Ctr
Prince George Cancer Info Ctr
Internet
Call Number
WP870 P951 2013
Website Notes
Patients and the public of BC and the Yukon can access this title by emailing library@bccancer.bc.ca or calling 1.888.675.8001 x 7000 (toll-free) to obtain a username and password.
Read Online
https://ebookcentral.proquest.com/lib/bccancer-ebooks/reader.action?docID=1036287

Copies

c.1 BC Cancer Agency VIC Cancer Info Ctr On Loan, due Thursday, June 20, 2024
c.1 BC Cancer Agency ARHCC Cancer Info Ctr Available
c.1 BC Cancer Agency PG Cancer Info Ctr Available
c.1 BC Cancer Agency KEL Cancer Info Ctr Available
c.1 BC Cancer Agency VAN Library Available
c.2 BC Cancer Agency KEL Cancer Info Ctr Available
Show Less

RNA interference screens to discover the Achilles heel of cancer

https://bccalibrary.andornot.com/en/permalink/catalog18122
Staudt, Louis M. [Vancouver, BC?]: BC Cancer Agency. Multi-Media Services , 2009.
Audience
Professional
Call Number
QZ206 B365 2009 v.267
Availability
1 copy, 1 available
More Information
Alternate Title
Monday noon seminar series
Author
Staudt, Louis M
Corporate Author
BC Cancer Research Centre Seminar Series
Place of Publication
[Vancouver, BC?]
Publisher
BC Cancer Agency. Multi-Media Services
Publication Date
2009
Physical Description
60 minutes
Series
BC Cancer Research Centre seminar series 267
Subjects
Lymphoma - genetics
B-Lymphocytes - immunology
Gene Expression Profiling
RNA Interference
NF-kappa B - metabolism
Language
English
Material Type
Video
DVD
Audience
Professional
Location
Vancouver Library AV Room
Call Number
QZ206 B365 2009 v.267

Copies

c.1 BC Cancer Agency VAN Library AV Room Available
Show Less

K-ras, HIF, and hypoxia in colon cancer

https://bccalibrary.andornot.com/en/permalink/catalog20642
Chung, Daniel C. [Vancouver, BC?]: BC Cancer Agency. Multi-Media Services , 2012.
Audience
Professional
Call Number
QZ206 B365 2012 v.321
Availability
1 copy, 1 available
More Information
Alternate Title
Monday noon seminar series
BCCA Research Seminar Series
Author
Chung, Daniel C
Corporate Author
BC Cancer Research Centre Seminar Series
Place of Publication
[Vancouver, BC?]
Publisher
BC Cancer Agency. Multi-Media Services
Publication Date
2012
Physical Description
60 minutes
Series
BC Cancer Research Centre seminar series 321
Subjects
Genes, Ras
Hypoxia-Inducible Factor 1
Cell Hypoxia
Colonic Neoplasms - metabolism
Neovascularization, Pathologic - genetics
Language
English
Material Type
Video
DVD
Audience
Professional
Location
Vancouver Library AV Room
Call Number
QZ206 B365 2012 v.321

Copies

c.1 BC Cancer Agency VAN Library AV Room Available
Show Less

Profiling copy number aberrations and loss of heterozygosity mutational landscapes in cancer genomes

https://bccalibrary.andornot.com/en/permalink/catalog21040
Ha, Gavin. [Vancouver, BC?]: BC Cancer Agency. Multi-Media Services , 2013.
Audience
Professional
Call Number
QZ206 B365 2013 v.326
Availability
1 copy, 1 available
More Information
Alternate Title
Monday noon seminar series
BCCA Research Seminar Series
Author
Ha, Gavin
Corporate Author
BC Cancer Research Centre Seminar Series
Place of Publication
[Vancouver, BC?]
Publisher
BC Cancer Agency. Multi-Media Services
Publication Date
2013
Physical Description
60 minutes
Series
BC Cancer Research Centre seminar series 326
Subjects
Loss of Heterozygosity - genetics
Chromosome Aberrations
Language
English
Material Type
Video
DVD
Audience
Professional
Location
Vancouver Library AV Room
Call Number
QZ206 B365 2013 v.326

Copies

c.1 BC Cancer Agency VAN Library AV Room Available
Show Less

Acute care oncology nursing

https://bccalibrary.andornot.com/en/permalink/catalog16574
[St. Louis, MO]: Saunders Elsevier , 2009. 2nd ed.
Audience
Professional
Call Number
WY161 A188c 2009
Availability
5 copies, 5 available
More Information
Editor
Chernecky, Cynthia C
Murphy-Ende, Kathleen
Edition
2nd ed.
Place of Publication
[St. Louis, MO]
Publisher
Saunders Elsevier
Publication Date
2009
Physical Description
xxv, 596 p. : ill. ; 24 cm.
Subjects
Oncology Nursing
Neoplasms - nursing
Critical Care - methods
Nurses' Instruction
ISBN
9781416037347 (hbk.)
1416037349 (hbk.)
Language
English
Material Type
Book
Audience
Professional
Location
Vancouver Library
Kelowna Library
Surrey Library
Victoria Library
Abbotsford Library
Call Number
WY161 A188c 2009

Copies

c.1 BC Cancer Agency ARHCC Library Available
c.1 BC Cancer Agency KEL Library Available
c.1 BC Cancer Agency SUR Library Available
c.1 BC Cancer Agency VAN Library Available
c.1 BC Cancer Agency VIC Library Available
Show Less

Patients' guide to leukemia

https://bccalibrary.andornot.com/en/permalink/catalog19528
Morrison, Candis, Hesdorffer, Charles S. Sudbury, MA: Jones and Bartlett Learning , 2011.
Audience
Patient or Public
Call Number
WH250 M878p 2011
Availability
5 copies, 5 available
More Information
  1 read online  
Alternate Title
Johns Hopkins patients' guide to leukemia
Author
Morrison, Candis
Hesdorffer, Charles S
Place of Publication
Sudbury, MA
Publisher
Jones and Bartlett Learning
Publication Date
2011
Physical Description
xii, 168 p. ; 21 cm.
Series
Proquest Ebook Central
Johns Hopkins patients' guide
ebrary books for public
Subjects
Leukemia
Popular Work
Notes
Surrey CIC keep 2022
ISBN
9780763774332
9781449618896
Language
English
Material Type
Book
Ebook
Audience
Patient or Public
Location
Vancouver Cancer Info Ctr
Kelowna Cancer Info Ctr
Surrey Cancer Info Ctr
Victoria Cancer Info Ctr
Abbotsford Cancer Info Ctr
Internet
Call Number
WH250 M878p 2011
Website Notes
Patients and the public of BC and the Yukon can access this title by emailing library@bccancer.bc.ca or calling 1.888.675.8001 x 7000 (toll-free) to obtain a username and password.
Read Online
https://ebookcentral.proquest.com/lib/bccancer-ebooks/reader.action?docID=3319191

Copies

c.1 BC Cancer Agency ARHCC Cancer Info Ctr Available
c.1 BC Cancer Agency KEL Cancer Info Ctr Available
c.1 BC Cancer Agency SUR Cancer Info Ctr Available
c.1 BC Cancer Agency VAN Cancer Info Ctr Available
c.1 BC Cancer Agency VIC Cancer Info Ctr Missing Available
Show Less

100 questions and answers about leukemia

https://bccalibrary.andornot.com/en/permalink/catalog20817
Ball, Edward D, Kagan, Alex. [Boston, MA]: Jones and Bartlett Publishers , 2013. 3rd ed.
Audience
Patient or Public
Call Number
WH250 B187 2013
Availability
9 copies, 8 available
More Information
  1 read online  
Alternate Title
One hundred questions and answers about leukemia
Author
Ball, Edward D
Kagan, Alex
Edition
3rd ed.
Place of Publication
[Boston, MA]
Publisher
Jones and Bartlett Publishers
Publication Date
2013
Physical Description
viii, 129 p. : ill. ; 23 cm.
Series
Proquest Ebook Central
ebrary books for public
100 questions & answers
Subjects
Leukemia
Popular Work
Notes
Surrey CIC keep 2022 (F0001912)
ISBN
9781449665838
9781449665845
Language
English
Material Type
Book
Ebook
Audience
Patient or Public
Location
Vancouver Cancer Info Ctr
Victoria Cancer Info Ctr
Abbotsford Cancer Info Ctr
Kelowna Cancer Info Ctr
Prince George Cancer Info Ctr
Internet
Call Number
WH250 B187 2013
Website Notes
Patients and the public of BC and the Yukon can access this title by emailing library@bccancer.bc.ca or calling 1.888.675.8001 x 7000 (toll-free) to obtain a username and password.
Read Online
https://ebookcentral.proquest.com/lib/bccancer-ebooks/reader.action?docID=3319295

Copies

c.2 BC Cancer Agency VIC Cancer Info Ctr On Loan, due Tuesday, June 11, 2024
c.1 BC Cancer Agency ARHCC Cancer Info Ctr Available
c.1 BC Cancer Agency PG Cancer Info Ctr Available
c.1 BC Cancer Agency KEL Cancer Info Ctr Available
c.1 BC Cancer Agency SUR Cancer Info Ctr Available
c.1 BC Cancer Agency VAN Cancer Info Ctr Available
c.2 BC Cancer Agency VAN Cancer Info Ctr Available
c.1 BC Cancer Agency VIC Cancer Info Ctr Available
c.2 BC Cancer Agency KEL Cancer Info Ctr Available
Show Less

20 records – page 1 of 1.