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20 records – page 1 of 1.

Mouse models of cancer : a laboratory manual

https://bccalibrary.andornot.com/en/permalink/catalog21838
Abate-Shen, Cory. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press , 2014.
Audience
Professional
Call Number
QZ200 M932a 2014
Availability
1 copy, 1 available
More Information
Author
Abate-Shen, Cory
Editor
Abate-Shen, Cory
Politi, Katerina
Chodosh, Lewis A
Olive, Kenneth P
Place of Publication
Cold Spring Harbor, NY
Publisher
Cold Spring Harbor Laboratory Press
Publication Date
2014
Physical Description
xiv, 521 p. : ill. ; 28 cm.
Subjects
Neoplasms - genetics
Neoplasms, Experimental
Disease Models, Animal
Models, Genetic
Mice, Transgenic
Laboratory Manuals
ISBN
9781621820031
Language
English
Material Type
Book
Audience
Professional
Location
Vancouver Library
Call Number
QZ200 M932a 2014

Copies

c.1 BC Cancer Agency VAN Library Available
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Some industrial chemical intermediates and solvents

https://bccalibrary.andornot.com/en/permalink/catalog122790
International Agency for Research on Cancer, IARC Working Group on the Identification of Carcinogenic Hazards to Humanss. Lyon, France: International Agency for Research on Cancer , 2020.
Audience
Professional
The IARC Monographs identify environmental factors that are carcinogenic hazards to humans. These include chemicals, complex mixtures, occupational exposures, physical agents, biological agents, and lifestyle factors. National health agencies can use this information as scientific support for their…
More Information
  2 read online  
Corporate Author
International Agency for Research on Cancer
IARC Working Group on the Identification of Carcinogenic Hazards to Humanss
Place of Publication
Lyon, France
Publisher
International Agency for Research on Cancer
Publication Date
2020
Series
IARC monographs on the evaluation of carcinogenic risks to humans 125
Subjects
Neoplasms - chemically induced
Solvents
Resins, synthetic
Occupational Exposure
Risk Factors
Abstract
The IARC Monographs identify environmental factors that are carcinogenic hazards to humans. These include chemicals, complex mixtures, occupational exposures, physical agents, biological agents, and lifestyle factors. National health agencies can use this information as scientific support for their actions to prevent exposure to potential carcinogens. - Website
ISBN
9789283201922
9789283201649
ISSN
1017-1606
Language
English
Material Type
Book
Online
Serial
Audience
Professional
Location
Internet
Website Notes
Available in PDF format.
Read Online
https://publications.iarc.fr/_publications/media/download/6081/72789a12410f17b9aa94581f0e9795bec1fe418c.pdf
https://monographs.iarc.fr/monographs-available/
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Identification of a genetic cause of aneuploidy in human cancer cells

https://bccalibrary.andornot.com/en/permalink/catalog20624
Solomon, David A. [Vancouver, BC?]: BC Cancer Agency. Multi-Media Services , 2012.
Audience
Professional
Call Number
QZ206 B365 2012 v.319
Availability
1 copy, 1 available
More Information
Alternate Title
Monday noon seminar series
BCCA Research Seminar Series
Author
Solomon, David A
Corporate Author
BC Cancer Research Centre Seminar Series
Place of Publication
[Vancouver, BC?]
Publisher
BC Cancer Agency. Multi-Media Services
Publication Date
2012
Physical Description
60 minutes
Series
BC Cancer Research Centre seminar series 319
Subjects
Aneuploidy
Chromosome Aberrations
Chromosomal Instability - genetics
Neoplasms - genetics
Antigens, Nuclear - genetics
STAG2 protein, human
Language
English
Material Type
Video
DVD
Audience
Professional
Location
Vancouver Library AV Room
Call Number
QZ206 B365 2012 v.319

Copies

c.1 BC Cancer Agency VAN Library AV Room Available
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Prognostic and predictive value of p53

https://bccalibrary.andornot.com/en/permalink/catalog13996
European School of Oncology. New York, NY: Elsevier , 1997.
Audience
Professional
Call Number
QZ202 P963 1997
Availability
1 copy, 1 available
More Information
Corporate Author
European School of Oncology
Editor
Klijn, Jan G. M
Place of Publication
New York, NY
Publisher
Elsevier
Publication Date
1997
Subjects
Predictive Value of Tests
Genes, p53
Neoplasms - genetics
Neoplasms - therapy
ISBN
044482832X
Language
English
Material Type
Book
Audience
Professional
Location
Vancouver Library
Call Number
QZ202 P963 1997

Copies

c.1 BC Cancer Agency VAN Library Available
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Molecular diagnostics of human cancer

https://bccalibrary.andornot.com/en/permalink/catalog4020
Cold Spring Harbor, N.Y.: Cold Spring Harbor Laboratory , 1989.
Audience
Professional
Call Number
QZ202 C217 1989 v.7
Availability
1 copy, 1 available
More Information
Editor
Furth, Mark
Greaves, Melvyn
Place of Publication
Cold Spring Harbor, N.Y.
Publisher
Cold Spring Harbor Laboratory
Publication Date
1989
Series
Cancer cells 7
Subjects
Neoplasms - diagnosis
Genetics, Biochemical - congresses
Oncogenes
Neoplasms - genetics
Growth Substances
ISBN
087969324X
Language
English
Material Type
Book
Audience
Professional
Location
Vancouver Library
Call Number
QZ202 C217 1989 v.7

Copies

c.1 BC Cancer Agency VAN Library Available
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Molecular basis of human cancer

https://bccalibrary.andornot.com/en/permalink/catalog119747
New York, NY: Springer Science+Business Media , 2017. 2nd ed.
Audience
Professional
Call Number
QZ202 M718 2017
Availability
3 copies, 3 available
More Information
Editor
Coleman, William B
Tsongalis, Gregory J
Edition
2nd ed.
Place of Publication
New York, NY
Publisher
Springer Science+Business Media
Publication Date
2017
Physical Description
xix, 873 p. : ill. ; 29 cm.
Subjects
Neoplasms - genetics
Cell Transformation, Neoplastic
Growth Substances - physiology
Molecular Medicine
ISBN
9781934115183
Language
English
Material Type
Book
Audience
Professional
Location
Vancouver Library
Surrey Library
Victoria Library
Call Number
QZ202 M718 2017

Copies

c.1 BC Cancer Agency VAN Library Available
c.1 BC Cancer Agency SUR Library Available
c.1 BC Cancer Agency VIC Library Available
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Chemicals, industrial processes and industries associated with cancer in humans

https://bccalibrary.andornot.com/en/permalink/catalog13997
International Agency for Research on Cancer. Lyon, France: International Agency for Research on Cancer , 1982.
Audience
Professional
Call Number
QZ202 I585 1982 Suppl 4
Availability
1 copy, 1 available
More Information
  2 read online  
Corporate Author
International Agency for Research on Cancer
Place of Publication
Lyon, France
Publisher
International Agency for Research on Cancer
Publication Date
1982
Series
IARC monographs on the evaluation of carcinogenic risks to humans suppl 4
Subjects
Neoplasms - genetics
Carcinogens
ISBN
9283214064
Language
English
Material Type
Book
Online
Audience
Professional
Location
Vancouver Library
Internet
Call Number
QZ202 I585 1982 Suppl 4
Read Online
http://monographs.iarc.fr/ENG/Monographs/suppl4/index.php
http://monographs.iarc.fr/ENG/Monographs/suppl4/Suppl4.pdf

Copies

c.1 BC Cancer Agency VAN Library Available
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Some organophosphate insecticides and herbicides

https://bccalibrary.andornot.com/en/permalink/catalog114756
International Agency for Research on Cancer, IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. Lyon, France: International Agency for Research on Cancer , 2017.
Audience
Professional
Call Number
QZ202 I585 2017 v. 112
Availability
1 copy, 1 available
This publication represents the views and expert; opinions of an IARC Working Group on the; Evaluation of Carcinogenic Risks to Humans which met in Lyon (France) March 2015.
More Information
  1 read online  
Corporate Author
International Agency for Research on Cancer
IARC Working Group on the Evaluation of Carcinogenic Risks to Humans
Place of Publication
Lyon, France
Publisher
International Agency for Research on Cancer
Publication Date
2017
Physical Description
vii, 451 p. : ill. ; 27 cm.
Series
IARC monographs on the evaluation of carcinogenic risks to humans 112
Subjects
Carcinogens
Neoplasms - chemically induced
Insecticides - toxicity
Pesticides - toxicity
Occupational Exposure
Malathion - toxicity
Parathion - toxicity
Diazinon - toxicity
Tetrachlorvinphos - toxicity
Abstract
This publication represents the views and expert
opinions of an IARC Working Group on the
Evaluation of Carcinogenic Risks to Humans which met in Lyon (France) March 2015.
Notes
IARC monographs are shelved in VC Journal stacks.
ISBN
9789283201502
ISSN
1017-1606
Language
English
French
Material Type
Book
Online
Audience
Professional
Location
Vancouver Library
Internet
Call Number
QZ202 I585 2017 v. 112
Website Notes
PDF and supplemental material available.
Read Online
http://monographs.iarc.fr/ENG/Monographs/vol112/index.php

Copies

c.1 BC Cancer Agency VAN Library Available
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Some aromatic amines, organic dyes, and related exposures

https://bccalibrary.andornot.com/en/permalink/catalog19912
International Agency for Research on Cancer, World Health Organization. Geneva: WHO Press , 2010.
Audience
Professional
Call Number
QZ202 I585 2010 v.99
Availability
1 copy, 1 available
More Information
  2 read online  
Corporate Author
International Agency for Research on Cancer
World Health Organization
Place of Publication
Geneva
Publisher
WHO Press
Publication Date
2010
Physical Description
viii, 678 p. : ill. ; 24 cm.
Series
IARC monographs on the evaluation of carcinogenic risks to humans 99
Subjects
Carcinogens
Neoplasms - chemically induced
Organic Chemicals - toxicity
Amines - toxicity
Barbering
Hair Dyes - toxicity
Coloring Agents - toxicity
Occupational Exposure
ISBN
9789283212997
9283212991
ISSN
1017-1606
Language
English
Material Type
Book
Online
Audience
Professional
Location
Vancouver Library
Internet
Call Number
QZ202 I585 2010 v.99
Read Online
http://monographs.iarc.fr/ENG/Monographs/vol99/index.php
http://monographs.iarc.fr/ENG/Monographs/vol99/mono99.pdf

Copies

c.1 BC Cancer Agency VAN Library Available
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Trichloroethylene, tetrachloroethylene, and some other chlorinated agents

https://bccalibrary.andornot.com/en/permalink/catalog21526
International Agency for Research on Cancer, IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. Lyon, France: International Agency for Research on Cancer , 2014.
Audience
Professional
More Information
  2 read online  
Corporate Author
International Agency for Research on Cancer
IARC Working Group on the Evaluation of Carcinogenic Risks to Humans
Place of Publication
Lyon, France
Publisher
International Agency for Research on Cancer
Publication Date
2014
Series
IARC monographs on the evaluation of carcinogenic risks to humans 106
Subjects
Carcinogens
Neoplasms - chemically induced
Occupational Exposure
Trichloroethylene - adverse effects
Trichloroacetic Acid - adverse effects
Tetrachloroethylene - adverse effects
Dichloroacetic Acid - adverse effects
Chloral Hydrate - adverse effects
ISBN
9789283201441
ISSN
1017-1606
Language
English
Material Type
Book
Online
Audience
Professional
Location
Internet
Read Online
http://monographs.iarc.fr/ENG/Monographs/vol106/index.php
http://monographs.iarc.fr/ENG/Monographs/vol106/mono106.pdf
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Some non-heterocyclic polycyclic aromatic hydrocarbons and some related exposures

https://bccalibrary.andornot.com/en/permalink/catalog18163
International Agency for Research on Cancer, World Health Organization. Lyon, France: International Agency for Research on Cancer , 2010.
Audience
Professional
Call Number
QZ202 I585 2010 v.92
Availability
1 copy, 1 available
More Information
  2 read online  
Corporate Author
International Agency for Research on Cancer
World Health Organization
Place of Publication
Lyon, France
Publisher
International Agency for Research on Cancer
Publication Date
2010
Physical Description
viii, 853 p. : ill. ; 24 cm.
Series
IARC monographs on the evaluation of carcinogenic risks to humans 92
Subjects
Carcinogens
Environmental Pollutants - toxicity
Neoplasms - etiology
Polycyclic Hydrocarbons, Aromatic - toxicity
Risk Assessment - methods
DNA Adducts
Environmental Exposure
Occupational Exposure
ISBN
9789283212928
ISSN
1017-1606
Language
English
Material Type
Book
Online
Audience
Professional
Location
Vancouver Library
Internet
Call Number
QZ202 I585 2010 v.92
Read Online
http://monographs.iarc.fr/ENG/Monographs/vol92/mono92.pdf
http://monographs.iarc.fr/ENG/Monographs/PDFs/index.php

Copies

c.1 BC Cancer Agency VAN Library Available
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Infections causing human cancer

https://bccalibrary.andornot.com/en/permalink/catalog15771
Zur Hausen, Harald. Weinheim: Wiley-VCH Verlag GMBH & Co. KGaA , 2006.
Audience
Professional
Call Number
QZ202 Z96 2006
Availability
1 copy, 1 available
More Information
Author
Zur Hausen, Harald
Place of Publication
Weinheim
Publisher
Wiley-VCH Verlag GMBH & Co. KGaA
Publication Date
2006
Subjects
Neoplasms - etiology
Neoplasms - genetics
Virus Diseases - complications
Virus Diseases - genetics
Cell Transformation, Neoplastic - genetics
Papillomavirus Infections
Helicobacter Infections
Epstein-Barr Virus Infections
Hepatitis
ISBN
9783527310562
3527310568
Language
English
Material Type
Book
Audience
Professional
Location
Vancouver Library
Call Number
QZ202 Z96 2006

Copies

c.1 BC Cancer Agency VAN Library Available
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Occupational exposures in insecticide application, and some pesticides

https://bccalibrary.andornot.com/en/permalink/catalog1431
International Agency for Research on Cancer. Lyon, France: International Agency for Research on Cancer , 1991.
Audience
Professional
Call Number
QZ202 I585 1991 v.53
Availability
1 copy, 1 available
More Information
  2 read online  
Corporate Author
International Agency for Research on Cancer
Place of Publication
Lyon, France
Publisher
International Agency for Research on Cancer
Publication Date
1991
Series
IARC Monographs on the Evaluation of Carcinogenic Risks to Humans 53
Subjects
Carcinogens - etiology
Occupational Exposure
Insecticides
Pesticides
ISBN
9283212533
Language
English
Material Type
Book
Online
Audience
Professional
Location
Vancouver Library
Internet
Call Number
QZ202 I585 1991 v.53
Read Online
http://monographs.iarc.fr/ENG/Monographs/vol53/index.php
http://monographs.iarc.fr/ENG/Monographs/vol53/mono53.pdf

Copies

c.1 BC Cancer Agency VAN Library Available
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Role of genetic testing in surgical oncology

https://bccalibrary.andornot.com/en/permalink/catalog113681
Philadelphia, PA: Elsevier , 2015.
Audience
Professional
Availability
1 copy, 1 available
More Information
Alternate Title
Surgical oncology clinics of North America v.24, no.4 October 2015
Editor
Weber, Thomas K.
Petrelli, Nicholas J
Place of Publication
Philadelphia, PA
Publisher
Elsevier
Publication Date
2015
Series
Surgical oncology clinics of North America v.24, no.4
Subjects
Genetic Testing
Genetic Counseling
Neoplasms - genetics
Neoplasms - surgery
Neoplastic Syndromes, Hereditary - genetics
ISBN
9780323401081
ISSN
1055-3207
Language
English
Material Type
Serial
Book
Audience
Professional
Location
Vancouver Library Journals

Copies

BC Cancer Agency VAN Library Available
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Review of human carcinogens : Part F : chemical agents and related occupations

https://bccalibrary.andornot.com/en/permalink/catalog20447
International Agency for Research on Cancer, World Health Organization. Lyon, France: International Agency for Research on Cancer , 2012.
Audience
Professional
Call Number
QZ202 I585 2012 v.100F
Availability
2 copies, 2 available
This publication represents the views and expert opinions of an IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, which met in Lyon, 29 September- October 6, 2009.
More Information
  2 read online  
Alternate Title
Chemical agents and related occupations
Corporate Author
International Agency for Research on Cancer
World Health Organization
Place of Publication
Lyon, France
Publisher
International Agency for Research on Cancer
Publication Date
2012
Physical Description
xvi, 599 p. : ill. ; 27 cm.
Series
IARC monographs on the evaluation of carcinogenic risks to humans 100F
Subjects
Carcinogens
Neoplasms - etiology
Air Pollution, Indoor
Food Preservation
Habits
Specialty Uses of Chemicals
Occupational Exposure
Abstract
This publication represents the views and expert opinions of an IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, which met in Lyon, 29 September- October 6, 2009.
ISBN
9789283213239
ISSN
1017-1606
Language
English
Material Type
Book
Online
Audience
Professional
Location
Vancouver Library
Victoria Library
Internet
Call Number
QZ202 I585 2012 v.100F
Read Online
http://monographs.iarc.fr/ENG/Monographs/PDFs/index.php
http://monographs.iarc.fr/ENG/Monographs/vol100F/index.php

Copies

c.1 BC Cancer Agency VAN Library Available
c.1 BC Cancer Agency VIC Library Available
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Man-made vitreous fibres

https://bccalibrary.andornot.com/en/permalink/catalog10319
International Agency for Research on Cancer. Lyon, France: International Agency for Research on Cancer , 2002.
Audience
Professional
Call Number
QZ202 I585 2002 v.81
Availability
1 copy, 1 available
More Information
  2 read online  
Corporate Author
International Agency for Research on Cancer
Place of Publication
Lyon, France
Publisher
International Agency for Research on Cancer
Publication Date
2002
Series
IARC monographs on the evaluation of carcinogenic risks to humans 81
Subjects
Mineral Fibers
Neoplasms - chemically induced
Occupational Exposure
Risk Assessment
Carcinogens
ISBN
9283212819
Language
English
Material Type
Book
Online
Audience
Professional
Location
Vancouver Library
Internet
Call Number
QZ202 I585 2002 v.81
Read Online
http://monographs.iarc.fr/ENG/Monographs/vol81/index.php
http://monographs.iarc.fr/ENG/Monographs/vol81/mono81.pdf

Copies

c.1 BC Cancer Agency VAN Library Available
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Occupational exposures of hairdressers and barbers and personal use of hair colourants; some hair dyes, cosmetic colourants, industrial dyestuffs and aromatic amines

https://bccalibrary.andornot.com/en/permalink/catalog1029
International Agency for Research on Cancer. Lyon, France: International Agency for Research on Cancer , 1993.
Audience
Professional
Call Number
QZ202 I585 1992 v.57
Availability
1 copy, 1 available
More Information
  2 read online  
Corporate Author
International Agency for Research on Cancer
Place of Publication
Lyon, France
Publisher
International Agency for Research on Cancer
Publication Date
1993
Series
IARC monographs on the evaluation of carcinogenic risks to humans 57
Subjects
Carcinogens
Hair Dyes - toxicity
Occupational Exposure
Hair Preparations
ISBN
9283212576
Language
English
Material Type
Book
Online
Audience
Professional
Location
Vancouver Library
Internet
Call Number
QZ202 I585 1992 v.57
Read Online
http://monographs.iarc.fr/ENG/Monographs/vol57/index.php
http://monographs.iarc.fr/ENG/Monographs/vol57/mono57.pdf

Copies

c.1 BC Cancer Agency VAN Library Available
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Occupational cancers

https://bccalibrary.andornot.com/en/permalink/catalog122394
Cham, Switzerland: Springer Nature Switzerland AG , 2020. 2nd ed.
Audience
Professional
Call Number
QZ202 O15 2020
Availability
2 copies, 2 available
Contents:; Historical Overview of Occupational Cancer Research -- Genetics and Gene-Environment Interactions -- Mechanisms of Environmental and Occupational Carcinogenesis -- Cancer of the Oral Cavity, Pharynx and Nasopharynx -- Pancreatic Cancer -- Cancers of the Intestine, Liver and Biliary Tract…
More Information
Editor
Sisko, Anttila
Boffetta, Paolo
Edition
2nd ed.
Place of Publication
Cham, Switzerland
Publisher
Springer Nature Switzerland AG
Publication Date
2020
Physical Description
xv, 640 p. : ill. ; 29 cm.
Subjects
Occupational Diseases
Occupational Health
Neoplasms - epidemiology
Neoplasms - chemically induced
Occupational Exposure
Abstract
Contents:
Historical Overview of Occupational Cancer Research -- Genetics and Gene-Environment Interactions -- Mechanisms of Environmental and Occupational Carcinogenesis -- Cancer of the Oral Cavity, Pharynx and Nasopharynx -- Pancreatic Cancer -- Cancers of the Intestine, Liver and Biliary Tract -- Sinonasal Cancer -- Laryngeal Cancer -- Lung cancer (exposure assessment, pathology, epidemiology) -- Lung Cancer: Mechanisms of Carcinogenesis -- Lung Cancer: Genetic Susceptibility -- Lung Cancer: Molecular Markers -- Malignant Mesothelioma: Epidemiology -- Malignant Mesothelioma: Clinical and Imaging Findings -- Malignant Mesothelioma: Asbestos Exposure -- Malignant Mesothelioma: Pathology -- Malignant Mesothelioma: Mechanism of Carcinogenesis -- Malignant Mesothelioma: Genetic Susceptibility -- Malignant Mesothelioma: Molecular Markers -- Neoplasm of Soft Tissues -- Malignant Neoplasms of the Skin -- Breast Cancer -- Malignant Tumors of the Female Reproductive System -- Malignant Tumors of the Male Reproductive System -- Kidney Cancer -- Bladder Cancer -- Malignant Tumors of the Central Nervous System -- Lymphohematopoietic Malignancies -- Occupational Cancer Burden -- Occupational Carcinogens and Cancer in Children -- Strategies for Primary Prevention of Occupational Cancer -- Screening for Occupational Cancer -- Role of Registers in Occupational Cancer Control -- Appendix I Questionnaire on Exposure to Asbestos.
ISBN
9783030307653
Language
English
Material Type
Book
Audience
Professional
Location
Vancouver Library
Victoria Library
Call Number
QZ202 O15 2020

Copies

c.1 BC Cancer Agency VAN Library Available
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Daughter of family G : a memoir of cancer genes, love and fate

https://bccalibrary.andornot.com/en/permalink/catalog123800
McKay, Ami. Toronto, ON: Alfred A. Knopf Canada , 2019.
Audience
Patient or Public
Call Number
QZ210 M478 2019
Availability
1 copy, 1 available
More Information
Author
McKay, Ami
Place of Publication
Toronto, ON
Publisher
Alfred A. Knopf Canada
Publication Date
2019
Physical Description
xvii, 299 p. : ill. ; 24 cm
Subjects
Neoplasms - genetics
Genetic Predisposition to Disease
Lynch Syndrome II
Genetic Testing
Neoplastic Syndromes, Hereditary
Personal Narratives
Popular Work
ISBN
9780345809469
Language
English
Material Type
Book
Audience
Patient or Public
Location
Vancouver Library
Call Number
QZ210 M478 2019

Copies

c.1 BC Cancer Agency VAN Library Available
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Cancer in the family : take control of your genetic inheritance

https://bccalibrary.andornot.com/en/permalink/catalog114763
Ross, Theodora. New York, NY: Avery , 2016.
Audience
Patient or Public
Call Number
QZ210 R826 2016
Availability
6 copies, 6 available
More Information
Author
Ross, Theodora
Place of Publication
New York, NY
Publisher
Avery
Publication Date
2016
Physical Description
xv, 286 p. : ill. ; 24 cm.
Subjects
Neoplasms - genetics
Genetic Predisposition to Disease
Genes, BRCA1
Genetic Counseling
Genetic Testing
Neoplastic Syndromes, Hereditary
Personal Narratives
Popular Work
ISBN
9781101982839
Language
English
Material Type
Book
Audience
Patient or Public
Location
Vancouver Library
Abbotsford Cancer Info Ctr
Kelowna Cancer Info Ctr
Prince George Cancer Info Ctr
Vancouver Cancer Info Ctr
Victoria Cancer Info Ctr
Call Number
QZ210 R826 2016
Website Notes
This resource was purchased with a donation from the Order of the Eastern Star.

Copies

c.1 BC Cancer Agency VIC Cancer Info Ctr Available
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c.1 BC Cancer Agency KEL Cancer Info Ctr Available
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20 records – page 1 of 1.