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20 records – page 1 of 1.

Topics in palliative care

https://bccalibrary.andornot.com/en/permalink/catalog8754
New York, NY: Oxford University Press , 1998.
Audience
Professional
Call Number
QZ266 T673 1998 v.3
Availability
1 copy, 1 available
Editor
Portendy, Russell K
Bruera, Eduardo
Place of Publication
New York, NY
Publisher
Oxford University Press
Publication Date
1998
Series
Topics in palliative care 3
Subjects
Palliative Care
Neoplasms - drug therapy
Pain - drug therapy
ISBN
0195102460
Language
English
Material Type
Book
Audience
Professional
Location
Vancouver Library
Call Number
QZ266 T673 1998 v.3

Copies

c.1 BC Cancer Agency VAN Library Available
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Integration of palliative care in chronic conditions: an interdisciplinary approach

https://bccalibrary.andornot.com/en/permalink/catalog120850
Oncology Nursing Society. Pittsburgh, PA: Oncology Nursing Society , 2017.
Audience
Professional
Table of Contents:; I Use of palliative care in chronic conditions and the Affordable Care Act -- Patient protection and the Affordable Care Act -- Patient-centered outcomes of care -- Self-management in chronic disease -- Care of multiple chronic conditions -- Comparative effectiveness research --…
  1 read online  
Corporate Author
Oncology Nursing Society
Editor
Kuebler, Kim K.
Place of Publication
Pittsburgh, PA
Publisher
Oncology Nursing Society
Publication Date
2017
Series
R2 Library
Subjects
Hospice and Palliative Care Nursing
Chronic Disease - nursing
Palliative Care - legislation & jurisprudence
Chronic Pain - nursing
Patient-Centered Care
Case Reports
United States
Abstract
Table of Contents:
I Use of palliative care in chronic conditions and the Affordable Care Act -- Patient protection and the Affordable Care Act -- Patient-centered outcomes of care -- Self-management in chronic disease -- Care of multiple chronic conditions -- Comparative effectiveness research -- Health policy and the role of advanced practice nurses -- II Pharmacology -- Metabolism and exretion in disease -- Cytochrome P450 in palliative care -- Drug-drug interaction in palliative care -- Palliative care and the concomitant medications -- III Chronic conditions and malignancy -- Cardiovascular diseases -- Chronic kidney disease -- Chronic obstructive pulmonary disease -- Endocrine disorders -- General oncology -- Musculoskeletal disorders: osteoarthritis -- Neurologic conditions -- IV Symptom management -- Anxiety -- Chronic nonmalignant pain -- Constipation -- Cough -- Dehydration -- Dementia -- Depression -- Dyspnea -- Insomnia -- Pruritus -- V Oncologic emergencies -- Hypercalcemia of malignancy -- malignant pleural effusion - Spinal cord compression -- Suprerior vena cava syndrome -- VI Palliative practices and patient and family communication -- Communicating with the patient and family -- Preparing the patient and family for the end of life -- Advance care planning -- Preparation versus crisis approach to care -- Identifying team disciplines -- Patient and family goal setting -- Interdisciplinary team collaboration, continuity, and communication -- VII Spritual support and self-care for professionals -- Spiritual and religious care -- Hope and loss -- Compassionate self-care: an interdisciplinary approach.
ISBN
1935864890
9781935864899
Language
English
Material Type
Ebook
Audience
Professional
Location
Internet
Website Notes
This R2 title is licensed for one BC Cancer staff user at a time only. Authentication via HealthBC sign in required. Use your BC Cancer staff username and ID when prompted.
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Commonly prescribed medications in radiation oncology

https://bccalibrary.andornot.com/en/permalink/catalog14566
Dziuk, Timothy W. Austin, TX: South Austin Cancer Center , 2005. 8th ed.
Audience
Professional
Call Number
QZ269 C734 2005
Availability
1 copy, 1 available
Author
Dziuk, Timothy W
Corporate Author
Texas Oncology, P.A. (Professional Association)
Edition
8th ed.
Place of Publication
Austin, TX
Publisher
South Austin Cancer Center
Publication Date
2005
Subjects
Radiotherapy - adverse effects
Neoplasms - radiotherapy
Neoplasms - drug therapy
Neoplasms - complications
Radiation Injuries - drug therapy
Palliative Care
Notes
CN Library copy is housed in the UHNBC Library.
Language
English
Material Type
Book
Audience
Professional
Location
CN Library
Call Number
QZ269 C734 2005

Copies

c.1 BC Cancer Agency CN Library Available
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Commonly prescribed medications in radiation oncology

https://bccalibrary.andornot.com/en/permalink/catalog18189
Dziuk, Timothy W. Austin, TX: Southwest Regional Cancer Centre , 2007. 9th ed.
Audience
Professional
Call Number
QZ269 C734 2007
Availability
4 copies, 4 available
Author
Dziuk, Timothy W
Corporate Author
Southwest Regional Cancer Center
Edition
9th ed.
Place of Publication
Austin, TX
Publisher
Southwest Regional Cancer Centre
Publication Date
2007
Subjects
Radiotherapy - adverse effects
Neoplasms - radiotherapy
Neoplasms - drug therapy
Neoplasms - complications
Radiation Injuries - drug therapy
Pharmaceutical Preparations
Palliative Care
Language
English
Material Type
Book
Audience
Professional
Location
Kelowna Library
Surrey Library
Victoria Library
Abbotsford Library
Call Number
QZ269 C734 2007

Copies

c.1 BC Cancer Agency ARHCC Library Available
c.1 BC Cancer Agency KEL Library Available
c.1 BC Cancer Agency SUR Library Available
c.1 BC Cancer Agency VIC Library Available
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Chemotherapy and biotherapy case studies

https://bccalibrary.andornot.com/en/permalink/catalog113731
Pittsburgh, Pa.: Oncology Nursing Society , 2015.
Audience
Professional
  1 read online  
Continues / Continued By
Continued by:
Chemotherapy and immunotherapy : guidelines and recommendations for practice
Editor
Polovich, Martha
Place of Publication
Pittsburgh, Pa.
Publisher
Oncology Nursing Society
Publication Date
2015
Series
R2 Library
Subjects
Oncology Nursing
Neoplasms - drug therapy
Drug therapy - nursing
Biological Therapy - nursing
ISBN
1935864610
9781935864615
9781935864660
Language
English
Material Type
Ebook
Audience
Professional
Location
Internet
Website Notes
This R2 title is licensed for one BC Cancer staff user at a time only. Authentication via HealthBC sign in required. Use your BC Cancer staff username and ID when prompted.
Read Online
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Platinum-based drugs in cancer therapy

https://bccalibrary.andornot.com/en/permalink/catalog19536
Totowa, NJ: Humana Press , 2000.
Audience
Professional
Call Number
QZ267 P716k 2000
Availability
1 copy, 1 available
Editor
Kelland, Lloyd R
Farrell, Nicholas P
Place of Publication
Totowa, NJ
Publisher
Humana Press
Publication Date
2000
Physical Description
xii, 341 p. : ill. ; 24 cm.
Series
Cancer drug discovery and development
Subjects
Antineoplastic Agents
Cisplatin
Neoplasms - drug therapy
Platinum Compounds - therapeutic use
ISBN
9780896035997
0896035999
Language
English
Material Type
Book
Audience
Professional
Location
Vancouver Library
Call Number
QZ267 P716k 2000

Copies

c.1 BC Cancer Agency VAN Library Available
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Chemistry and evaluation of porphyrin-based potential anti-cancer agents

https://bccalibrary.andornot.com/en/permalink/catalog14035
Posakony, Jeffrey Jerard. [Vancouver, BC?]: University of British Columbia , 1998.
Audience
Professional
Call Number
LE3 1998 P885
Availability
1 copy, 1 available
Author
Posakony, Jeffrey Jerard
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1998
Subjects
Antineoplastic Agents - administration & dosage
Neoplasms - drug therapy
Porphyrins
Language
English
Material Type
Book
Thesis
Audience
Professional
Location
Vancouver Library
Call Number
LE3 1998 P885

Copies

c.1 BC Cancer Agency VAN Library Available
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Advancing medicine through clinical trials

https://bccalibrary.andornot.com/en/permalink/catalog18271
Pfizer. Kirkland, QC: Pfizer Inc. , 2009?.
Audience
Patient or Public
Call Number
HA29 A244 2009
Availability
1 copy, 1 available
Introduction; Importance, benefits and risks of clinical trials; Four phases of clinical trials; Your role as a participant; Safety aspects of a clinical trial; Conclusion
Corporate Author
Pfizer
Place of Publication
Kirkland, QC
Publisher
Pfizer Inc.
Publication Date
2009?
Subjects
Clinical Trials as Topic
Neoplasms - drug therapy
Patient Education as Topic
Decision Making
Popular Work
Abstract
Introduction
Importance, benefits and risks of clinical trials
Four phases of clinical trials
Your role as a participant
Safety aspects of a clinical trial
Conclusion
Language
English
Material Type
Video
DVD
Audience
Patient or Public
Location
Vancouver Library
Call Number
HA29 A244 2009

Copies

c.1 BC Cancer Agency VAN Library Available
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Cancer pain : assessment, diagnosis, and management

https://bccalibrary.andornot.com/en/permalink/catalog18865
Fitzgibbon, Dermot R, Loeser, John D. Philadelphia, PA: Wolters Kluwer Health/Lippincott Williams & Wilkins , 2010.
Audience
Professional
Call Number
WL700 F554c 2010
Availability
4 copies, 4 available
Author
Fitzgibbon, Dermot R
Loeser, John D
Place of Publication
Philadelphia, PA
Publisher
Wolters Kluwer Health/Lippincott Williams & Wilkins
Publication Date
2010
Physical Description
x, 378 p. : ill. ; 29 cm.
Subjects
Pain - drug therapy
Neoplasms - drug therapy
Neoplasms - diagnosis
Pain Measurement
Notes
CN Library copy is housed in the UHNBC Library.
ISBN
9781608310890
1608310892
Language
English
Material Type
Book
Audience
Professional
Location
Vancouver Library
Kelowna Library
Abbotsford Library
CN Library
Call Number
WL700 F554c 2010

Copies

c.1 BC Cancer Agency ARHCC Library Available
c.1 BC Cancer Agency CN Library Available
c.1 BC Cancer Agency KEL Library Available
c.1 BC Cancer Agency VAN Library Available
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Physicians' cancer chemotherapy drug manual 2023

https://bccalibrary.andornot.com/en/permalink/catalog125034
Burlington, MA: Jones & Bartlett Learning, LLC , 2023. 23rd ed.
Audience
Professional
"Completely revised and updated for 2023, the Physicians' Cancer Chemotherapy Drug Manual is an up-to-date guide to the latest information on standard therapy and recent advances in the field. Written by world-class experts in clinical cancer therapeutics, this essential reference provides a comple…
  1 read online  
Editor
Chu, Edward
DeVita, Vincent T., Jr.
Edition
23rd ed.
Place of Publication
Burlington, MA
Publisher
Jones & Bartlett Learning, LLC
Publication Date
2023
Series
R2 Library
Subjects
Antineoplastic Agents
Neoplasms - drug therapy
Handbook
Abstract
"Completely revised and updated for 2023, the Physicians' Cancer Chemotherapy Drug Manual is an up-to-date guide to the latest information on standard therapy and recent advances in the field. Written by world-class experts in clinical cancer therapeutics, this essential reference provides a complete, easy-to-use catalogue of over 100 drugs and commonly used drug regimens-both on- and off-label-for the treatment of all the major cancers." -- Provided by publisher
ISBN
1284272737
9781284272734
9781284272741
Language
English
Material Type
Ebook
Audience
Professional
Location
Internet
Website Notes
This R2 title is licensed for one BC Cancer staff user at a time only. Authentication via HealthBC sign in required. Use your BC Cancer staff username and ID when prompted.
Read Online
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Concise manual of hematology and oncology

https://bccalibrary.andornot.com/en/permalink/catalog16084
New York, NY: Springer , 2008.
Audience
Professional
Call Number
WH100 C744 2008
Availability
1 copy, 1 available
Editor
Berger, Dietmar P
Place of Publication
New York, NY
Publisher
Springer
Publication Date
2008
Physical Description
xxi, 1004 p. : ill. ; 24 cm.
Subjects
Hematologic Neoplasms
Medical Oncology
Neoplasms - drug therapy
Hematologic Diseases
Hematology
ISBN
9783540732761
3540732764
Language
English
Material Type
Book
Audience
Professional
Location
Vancouver Library
Call Number
WH100 C744 2008

Copies

c.1 BC Cancer Agency VAN Library Available
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Physicians' cancer chemotherapy drug manual 2021

https://bccalibrary.andornot.com/en/permalink/catalog123246
Chu, Edward, DeVita, Vincent T., Jr. Burlington, MA: Jones and Bartlett Learning , 2022. 21st ed.
Audience
Professional
  1 read online  
Author
Chu, Edward
DeVita, Vincent T., Jr.
Edition
21st ed.
Place of Publication
Burlington, MA
Publisher
Jones and Bartlett Learning
Publication Date
2022
Series
R2 Library
Subjects
Neoplasms - drug therapy
Antineoplastic Agents - therapeutic use
ISBN
1284230139
9781284230130
9781284230284
Language
English
Material Type
Ebook
Audience
Professional
Location
Internet
Website Notes
This R2 title is licensed for one BC Cancer staff user at a time only. Authentication via HealthBC sign in required. Use your BC Cancer staff username and ID when prompted.
Read Online
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Physicians' cancer chemotherapy drug manual 2020

https://bccalibrary.andornot.com/en/permalink/catalog122332
Chu, Edward, DeVita, Vincent T., Jr. Burlington, MA: Jones and Bartlett Learning , [2020]. 20th ed.
Audience
Professional
Call Number
QZ267 C559 2020
Availability
1 copy, 1 available
  1 read online  
Author
Chu, Edward
DeVita, Vincent T., Jr.
Edition
20th ed.
Place of Publication
Burlington, MA
Publisher
Jones and Bartlett Learning
Publication Date
[2020]
Physical Description
ix, 751 p. : ill. ; 23 cm.
Series
Proquest Ebook Central
Subjects
Neoplasms - drug therapy
Antineoplastic Agents - therapeutic use
ISBN
9781284198041
9781284198058
Language
English
Material Type
Book
Ebook
Audience
Professional
Location
Internet
Surrey Library
Call Number
QZ267 C559 2020
Website Notes
This Proquest title is licensed for ONE BC Cancer staff user at a time. If you are denied access while on a network computer, please try again later.
Authentication via HealthBC sign in required. Use your BC Cancer staff username and ID when prompted.
Read Online

Copies

c.1 BC Cancer Agency SUR Library Available
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Grief recovery for teens : letting go of painful emotions with body-based practices

https://bccalibrary.andornot.com/en/permalink/catalog121068
Popowitz, Coral. Oakland, CA: Instant Help Books , 2017.
Audience
Patient or Public
Call Number
BF575 G7 P829 2017
Availability
4 copies, 4 available
Author
Popowitz, Coral
Place of Publication
Oakland, CA
Publisher
Instant Help Books
Publication Date
2017
Physical Description
x, 198 p. ; 20 cm.
Series
Instant help solutions
Subjects
Grief
Emotions
Psychology, Adolescent
Mind Body Therapies
Adolescent
Juvenile Literature
Notes
Surrey CIC keep 2022
ISBN
9781626258532
1626258538
Language
English
Material Type
Book
Audience
Patient or Public
Location
Abbotsford Cancer Info Ctr
Kelowna Cancer Info Ctr
Surrey Cancer Info Ctr
Victoria Cancer Info Ctr
Call Number
BF575 G7 P829 2017
Website Notes
This resource was purchased with a donation from the Order of the Eastern Star.

Copies

c.1 BC Cancer Agency SUR Cancer Info Ctr Available
c.1 BC Cancer Agency ARHCC Cancer Info Ctr Available
c.1 BC Cancer Agency KEL Cancer Info Ctr Available
c.1 BC Cancer Agency VIC Cancer Info Ctr Available
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Yoga for pain relief : simple practices to calm your mind and heal your chronic pain

https://bccalibrary.andornot.com/en/permalink/catalog21583
McGonigal, Kelly. Oakland, CA: New Harbinger Publications , 2009.
Audience
Patient or Public
Call Number
QZ266 M113 2009
Availability
3 copies, 3 available
Author
McGonigal, Kelly
Place of Publication
Oakland, CA
Publisher
New Harbinger Publications
Publication Date
2009
Physical Description
x, 182 p. : ill. ; 26 cm.
Series
Whole body healing
Subjects
Yoga
Chronic Pain
Meditation
Exercise Therapy
Breathing Exercises
Mind Body Therapies
Stress, Psychological
Complementary Therapies
Popular Work
ISBN
9781572246898
Language
English
Material Type
Book
Audience
Patient or Public
Location
Abbotsford Cancer Info Ctr
Victoria Cancer Info Ctr
Vancouver Library
Call Number
QZ266 M113 2009
Website Notes
This resource was purchased with a donation from the Order of the Eastern Star.

Copies

c.1 BC Cancer Agency VIC Cancer Info Ctr Available
c.1 BC Cancer Agency ARHCC Cancer Info Ctr Missing Available
c.1 BC Cancer Agency VAN Library Available
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Death of cancer : after fifty years on the front lines of medicine, a pioneering oncologist reveals why the war on cancer is winnable--and how we can get there

https://bccalibrary.andornot.com/en/permalink/catalog113763
DeVita, Vincent T. Jr., DeVita-Raeburn, Elizabeth. New York, NY: Farrar, Straus and Giroux , 2015.
Audience
Patient or Public
Call Number
QZ11.1 D496 2015
Availability
4 copies, 4 available
Author
DeVita, Vincent T. Jr.
DeVita-Raeburn, Elizabeth
Place of Publication
New York, NY
Publisher
Farrar, Straus and Giroux
Publication Date
2015
Physical Description
324 p., [16] p. of plates ; 24 cm.
Subjects
Neoplasms - history
Neoplasms - drug therapy
Medical Oncology - history
Biomedical Research
Antineoplastic Agents - history
History of Medicine
United States
Autobiography
Notes
Table of Contents:
Introduction
Outrageous fortune
The chemotherapists
MOMP
MOPP
The war on cancer
Boots on the ground
Cleaning house at the National Cancer Institute
Frances Kelsey syndrome
Where rubber meets the road
The death of cancer
Outrageous fortune part II.
ISBN
9780374135607
Language
English
Material Type
Book
Audience
Patient or Public
Location
Vancouver Library
Abbotsford Cancer Info Ctr
Victoria Cancer Info Ctr
Kelowna Cancer Info Ctr
Call Number
QZ11.1 D496 2015

Copies

c.1 BC Cancer Agency VAN Library Available
c.1 BC Cancer Agency ARHCC Cancer Info Ctr Available
c.1 BC Cancer Agency KEL Cancer Info Ctr Available
c.1 BC Cancer Agency VIC Cancer Info Ctr Available
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Being well (even when you're sick) : mindfulness practices for people with cancer and other serious illnesses

https://bccalibrary.andornot.com/en/permalink/catalog20870
Rosenbaum, Elana. [Boston, MA]: Shambhala , 2012.
Audience
Patient or Public
Call Number
QZ266 R813b 2012
Availability
8 copies, 8 available
  1 read online  
Author
Rosenbaum, Elana
Place of Publication
[Boston, MA]
Publisher
Shambhala
Publication Date
2012
Physical Description
xiii, 150 p. ; 20 cm.
Subjects
Neoplasms - therapy
Neoplasms - psychology
Mind Body Therapies
Self Care
Complementary Therapies
Popular Work
Notes
Surrey CIC keep 2022 PFC
ISBN
9781611800005
Language
English
Material Type
Book
Audience
Patient or Public
Location
Vancouver Cancer Info Ctr
Kelowna Cancer Info Ctr
Surrey Cancer Info Ctr
Victoria Cancer Info Ctr
Abbotsford Cancer Info Ctr
Prince George Cancer Info Ctr
Call Number
QZ266 R813b 2012
Website Notes
Audio files that accompany some of the exercises in this book
Read Online

Copies

c.1 BC Cancer Agency ARHCC Cancer Info Ctr Available
c.1 BC Cancer Agency PG Cancer Info Ctr Available
c.1 BC Cancer Agency KEL Cancer Info Ctr Available
c.2 BC Cancer Agency KEL Cancer Info Ctr Available
c.1 BC Cancer Agency SUR Cancer Info Ctr Surrey PFC Available
c.1 BC Cancer Agency VAN Cancer Info Ctr Available
c.1 BC Cancer Agency VIC Cancer Info Ctr Missing Available
c.2 BC Cancer Agency VIC Cancer Info Ctr Available
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The power of imagery : optimizing cancer treatments

https://bccalibrary.andornot.com/en/permalink/catalog121095
Rossman, Martin L. [United States]: The Healing Mind, Inc. , 2005.
Audience
Patient or Public
Call Number
QZ266 R837o 2005
Availability
2 copies, 2 available
1. Intro: optimizing cancer treatment; 2. Making the most of chemotherapy; 3. Making the most of radiotherapy; 4. Your all-inclusive healing imagery; 5. Closing
Alternate Title
Optimizing cancer treatments
Author
Rossman, Martin L.
Place of Publication
[United States]
Publisher
The Healing Mind, Inc.
Publication Date
2005
Physical Description
1 audio disc : approx. 72 min.
Subjects
Neoplasms - therapy
Neoplasms - drug therapy
Neoplasms - psychology
Imagery (Psychotherapy)
Relaxation Therapy
Mind-Body Therapies
Popular Work
Abstract
1. Intro: optimizing cancer treatment
2. Making the most of chemotherapy
3. Making the most of radiotherapy
4. Your all-inclusive healing imagery
5. Closing
Notes
"Learn to use your mind-body connection for healing" - Cover
ISBN
0977349489
Language
English
Material Type
Audio
CD
Audience
Patient or Public
Location
Vancouver Library Relax
Kelowna Cancer Info Ctr
Call Number
QZ266 R837o 2005
Website Notes
This resource was purchased with a donation from the Order of the Eastern Star.

Copies

c.1 BC Cancer Agency VC Library Relax Available
c.1 BC Cancer Agency KEL Cancer Info Ctr Available
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A beginner's guide to targeted cancer treatments

https://bccalibrary.andornot.com/en/permalink/catalog121358
Vickers, Elaine. Hoboken, NJ: Wiley Blackwell , 2018.
Audience
Professional
Patient or Public
Call Number
QZ267 V637 2018
Availability
1 copy, 1 available
Author
Vickers, Elaine
Place of Publication
Hoboken, NJ
Publisher
Wiley Blackwell
Publication Date
2018
Physical Description
xii, 343 p. : col. ill. ; 26 cm.
Subjects
Neoplasms - drug therapy
Molecular Targeted Therapy - methods
ISBN
9781119126799
Language
English
Material Type
Book
Audience
Professional
Patient or Public
Location
Vancouver Library
Call Number
QZ267 V637 2018
Loan Policy
28 days

Copies

c.1 BC Cancer Agency VAN Library Available
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Optimizing chemotherapy

https://bccalibrary.andornot.com/en/permalink/catalog19821
Miller, Emmett. Los Altos, Ca: Emmett Miller , 2008.
Audience
Patient or Public
Call Number
QZ266 M648o 2008
Availability
9 copies, 9 available
Relaxation and healing; Healing cancer; Maximizing chemotherapy
Alternate Title
Optimizing chemotherapy : deep relaxation, guided imagery, music, self-healing
Author
Miller, Emmett
Place of Publication
Los Altos, Ca
Publisher
Emmett Miller
Publication Date
2008
Physical Description
49 minutes
Subjects
Neoplasms - drug therapy
Imagery (Psychotherapy)
Adaptation, Psychological
Relaxation Therapy
Mental Healing
Music Therapy
Popular Work
Abstract
Relaxation and healing
Healing cancer
Maximizing chemotherapy
ISBN
9781558410046
Language
English
Material Type
Audio
CD
Audience
Patient or Public
Location
Vancouver Library Relax
Kelowna Cancer Info Ctr
Victoria Cancer Info Ctr
Abbotsford Cancer Info Ctr
Prince George Cancer Info Ctr
Call Number
QZ266 M648o 2008

Copies

c.1 BC Cancer Agency ARHCC Cancer Info Ctr Available
c.2 BC Cancer Agency ARHCC Cancer Info Ctr Available
c.1 BC Cancer Agency PG Cancer Info Ctr Available
c.1 BC Cancer Agency KEL Cancer Info Ctr Available
c.2 BC Cancer Agency KEL Cancer Info Ctr Available
c.1 BC Cancer Agency VC Library Relax Available
c.2 BC Cancer Agency VC Library Relax Available
c.1 BC Cancer Agency VIC Cancer Info Ctr Available
c.2 BC Cancer Agency VIC Cancer Info Ctr Available
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20 records – page 1 of 1.