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20 records – page 1 of 1.

Targeted therapies for cancer

https://bccalibrary.andornot.com/en/permalink/catalog17575
Krystal, Gerald. [Vancouver, BC?]: BC Cancer Agency. Multi-Media Services , 2008.
Audience
Professional
Call Number
QZ206 B365 2008 v.256
Availability
1 copy, 1 available
More Information
Alternate Title
Monday noon seminar series
Author
Krystal, Gerald
Corporate Author
BC Cancer Research Centre Seminar Series
Place of Publication
[Vancouver, BC?]
Publisher
BC Cancer Agency. Multi-Media Services
Publication Date
2008
Physical Description
60 minutes
Series
BC Cancer Research Centre seminar series 256
Subjects
Neoplasms - therapy
Antibodies, Monoclonal
Immunotherapy
Gene Therapy
Language
English
Material Type
Video
DVD
Audience
Professional
Location
Vancouver Library AV Room
Call Number
QZ206 B365 2008 v.256

Copies

c.1 BC Cancer Agency VAN Library AV Room Available
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Administering Rituxan (rituximab) : a practical guide

https://bccalibrary.andornot.com/en/permalink/catalog18131
Hewitt, Karen, Zanke, Brent, Berinstein, Neil. Mississauga, ON: Hoffmann-La Roche Limited , 2000.
Audience
Patient or Public
Call Number
QZ267 A238 2000
Availability
1 copy, 1 available
More Information
Author
Hewitt, Karen
Zanke, Brent
Berinstein, Neil
Place of Publication
Mississauga, ON
Publisher
Hoffmann-La Roche Limited
Publication Date
2000
Physical Description
colour ; 15 minutes
Subjects
Antibodies, Monoclonal - therapeutic use
Lymphoma, Non-Hodgkin - therapy
Antineoplastic Agents - administration & dosage
Language
English
Material Type
DVD
Video
Audience
Patient or Public
Location
Vancouver Library
Call Number
QZ267 A238 2000

Copies

c.1 BC Cancer Agency VAN Library Available
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RANK ligand : a key signal in cancer-induced bone disease and hormone ablative therapy-induced bone loss

https://bccalibrary.andornot.com/en/permalink/catalog19811
Amgen Inc. Thousand Oaks, Calif.: Amgen Inc. , 2009.
Audience
Professional
Call Number
WE258 R198 2009
Availability
1 copy, 1 available
Introduction; RANK ligand in bone biology; Bone metastases; Multiple myeloma; Skeletal-related events (SREs); Hormone ablative therapy-induced bone loss
More Information
Author
Amgen Inc.
Place of Publication
Thousand Oaks, Calif.
Publisher
Amgen Inc.
Publication Date
2009
Subjects
RANK Ligand - metabolism
Osteoblasts
Osteoclasts
Antibodies, Monoclonal - therapeutic use
Bone Neoplasms - secondary
Bone Resorption
Osteoporosis - therapy
Antineoplastic Agents, Hormonal - adverse effects
Abstract
Introduction
RANK ligand in bone biology
Bone metastases
Multiple myeloma
Skeletal-related events (SREs)
Hormone ablative therapy-induced bone loss
Language
English
Material Type
Video
DVD
Audience
Professional
Location
Abbotsford Library
Call Number
WE258 R198 2009

Copies

c.1 BC Cancer Agency ARHCC Library Available
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Treating early breast cancer : BC Cancer Agency policies|Evolution in funding new cancer drugs

https://bccalibrary.andornot.com/en/permalink/catalog16246
Ellard, Susan, O'Reilly, Susan. [Vancouver, BC?]: BC Cancer Agency. Multi-Media Services , 2006.
Audience
Professional
Call Number
QZ200 B366a 2006 v.2
Availability
2 copies, 2 available
Full conference information obtained from the Annual cancer conference program and abstracts. See ID# 15548. (QZ200 B366 2006); Treating early breast cancer : BC Cancer Agency policies by Dr. Susan Ellard (25 minutes); Evolution in funding new cancer drugs by Dr. Susan O'Reilly (25 minutes)
More Information
Alternate Title
Annual cancer conference
Annual cancer conference : partners in research and care : BC and the world
Author
Ellard, Susan
O'Reilly, Susan
Corporate Author
BC Cancer Agency. Annual Cancer Conference (2006 November 23-25 : Vancouver, BC)
Place of Publication
[Vancouver, BC?]
Publisher
BC Cancer Agency. Multi-Media Services
Publication Date
2006
Physical Description
50 minutes
Series
BC Cancer Agency annual cancer conference 2006 v.2
Subjects
Breast Neoplasms - therapy
Antineoplastic Agents - economics
Drugs - economics
Delivery of Health Care - economics
BC Cancer Agency
Abstract
Full conference information obtained from the Annual cancer conference program and abstracts. See ID# 15548. (QZ200 B366 2006)
Treating early breast cancer : BC Cancer Agency policies by Dr. Susan Ellard (25 minutes)
Evolution in funding new cancer drugs by Dr. Susan O'Reilly (25 minutes)
Language
English
Material Type
Video
DVD
Audience
Professional
Location
Victoria Library
Vancouver Library AV Room
Call Number
QZ200 B366a 2006 v.2

Copies

c.1 BC Cancer Agency VAN Library AV Room Available
c.1 BC Cancer Agency VIC Library Available
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Novel multi-targeted approach for the treatment of solid tumours at the advanced stages

https://bccalibrary.andornot.com/en/permalink/catalog17625
Jean-Claude, Bertrand J. [Vancouver, BC?]: BC Cancer Agency. Multi-Media Services , 2008.
Audience
Professional
Call Number
QZ206 B365 2008 v.258
Availability
1 copy, 1 available
More Information
Alternate Title
Monday noon seminar series
Author
Jean-Claude, Bertrand J
Corporate Author
BC Cancer Research Centre Seminar Series
Place of Publication
[Vancouver, BC?]
Publisher
BC Cancer Agency. Multi-Media Services
Publication Date
2008
Physical Description
60 minutes
Series
BC Cancer Research Centre seminar series 258
Subjects
Neoplasms - drug therapy
Antineoplastic Agents - pharmacology
DNA-Binding Proteins
Receptor, Epidermal Growth Factor
DNA Damage
Models, Molecular
Language
English
Material Type
Video
DVD
Audience
Professional
Location
Vancouver Library AV Room
Call Number
QZ206 B365 2008 v.258

Copies

c.1 BC Cancer Agency VAN Library AV Room Available
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Novel targeted therapies for bladder cancer using an intravesical approach

https://bccalibrary.andornot.com/en/permalink/catalog18320
So, Alan. [Vancouver, BC?]: BC Cancer Agency. Multi-Media Services , 2009.
Audience
Professional
Call Number
QZ206 B365 2009 v.278
Availability
1 copy, 1 available
More Information
Alternate Title
Monday noon seminar series
Author
So, Alan
Corporate Author
BC Cancer Research Centre Seminar Series
Place of Publication
[Vancouver, BC?]
Publisher
BC Cancer Agency. Multi-Media Services
Publication Date
2009
Physical Description
60 minutes
Series
BC Cancer Research Centre seminar series 278
Subjects
Urinary Bladder Neoplasms - drug therapy
Administration, Intravesical
Language
English
Material Type
Video
DVD
Audience
Professional
Location
Vancouver Library AV Room
Call Number
QZ206 B365 2009 v.278

Copies

c.1 BC Cancer Agency VAN Library AV Room Available
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Latest in cancer treatments : participating in clinical trials

https://bccalibrary.andornot.com/en/permalink/catalog16277
Lee, Ursula. [Vancouver, BC?]: BC Cancer Agency. Multi-Media Services , 2006.
Audience
Patient or Public
Call Number
QZ200 B366a 2006 v.18
Availability
2 copies, 2 available
Full conference information obtained from the Annual cancer conference program and abstracts. See ID# 15548. (QZ200 B366 2006)
More Information
Alternate Title
Annual cancer conference
Annual cancer conference : partners in research and care : BC and the world
BC Cancer Agency Community Cancer Forum
Author
Lee, Ursula
Corporate Author
BC Cancer Agency. Annual Cancer Conference (2006 November 23-25 : Vancouver, BC)
Place of Publication
[Vancouver, BC?]
Publisher
BC Cancer Agency. Multi-Media Services
Publication Date
2006
Physical Description
120 minutes
Series
BC Cancer Agency annual cancer conference 2006 v.18
Subjects
Neoplasms - therapy
Clinical Trials
BC Cancer Agency
Popular Work
Abstract
Full conference information obtained from the Annual cancer conference program and abstracts. See ID# 15548. (QZ200 B366 2006)
Language
English
Material Type
Video
DVD
Audience
Patient or Public
Location
Vancouver Library
Victoria Library
Call Number
QZ200 B366a 2006 v.18

Copies

c.1 BC Cancer Agency VAN Library Available
c.1 BC Cancer Agency VIC Library Available
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Part 1: The Pleiades project and targeted gene replacement in Huntington disease|Part 2: Towards a prophylactic tumor vaccine using a canine model system

https://bccalibrary.andornot.com/en/permalink/catalog16240
Holt, Robert. [Vancouver, BC?]: BC Cancer Agency. Multi-Media Services , 2008.
Audience
Professional
Call Number
QZ206 B365 2008 v.243
Availability
1 copy, 1 available
More Information
Alternate Title
Monday noon seminar series
Author
Holt, Robert
Corporate Author
BC Cancer Research Centre Seminar Series
Place of Publication
[Vancouver, BC?]
Publisher
BC Cancer Agency. Multi-Media Services
Publication Date
2008
Physical Description
60 minutes
Series
BC Cancer Research Centre seminar series 243
Subjects
Targeted Gene Repair
Huntington Disease
Cancer Vaccines
Language
English
Material Type
Video
DVD
Audience
Professional
Location
Vancouver Library AV Room
Call Number
QZ206 B365 2008 v.243

Copies

c.1 BC Cancer Agency VAN Library AV Room Available
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Breast cancer : treatment of the lymph nodes ;|Psychosocial oncology : what's new for breast cancer patients and survivors ;|Adherence to hormonal therapy in breast cancer

https://bccalibrary.andornot.com/en/permalink/catalog18405
Berrang, Tanya, Stephen, Joanne, Chia, Stephen. [Vancouver, BC?]: BC Cancer Agency. Multi-Media Services , 2009.
Audience
Patient or Public
Call Number
WP870 B863 2009 v.14
Availability
8 copies, 8 available
Breast cancer : treatment of the lymph nodes by Dr. Tanya Berrang; Psychosocial oncology : what's new for breast cancer patients and survivors by Dr. Joanne Stephen; Adherence to hormonal therapy in breast cancer by Dr. Stephen Chia.
More Information
Author
Berrang, Tanya
Stephen, Joanne
Chia, Stephen
Corporate Author
BC Cancer Agency. Breast Tumour Group
Place of Publication
[Vancouver, BC?]
Publisher
BC Cancer Agency. Multi-Media Services
Publication Date
2009
Physical Description
60 minutes
Series
BCCA video telehealth series "Closer to home" 14
Subjects
Breast Neoplasms - psychology
Breast Neoplasms - drug therapy
Breast Neoplasms - rehabilitation
Breast Neoplasms - radiotherapy
Lymph Nodes
Antineoplastic Agents, Hormonal
Social Support
Popular Work
Abstract
Breast cancer : treatment of the lymph nodes by Dr. Tanya Berrang
Psychosocial oncology : what's new for breast cancer patients and survivors by Dr. Joanne Stephen
Adherence to hormonal therapy in breast cancer by Dr. Stephen Chia.
Language
English
Material Type
Video
DVD
Audience
Patient or Public
Location
Vancouver Library
Kelowna Cancer Info Ctr
Victoria Cancer Info Ctr
Abbotsford Cancer Info Ctr
Call Number
WP870 B863 2009 v.14

Copies

c.1 BC Cancer Agency ARHCC Cancer Info Ctr Available
c.2 BC Cancer Agency ARHCC Cancer Info Ctr Available
c.1 BC Cancer Agency KEL Cancer Info Ctr Available
c.2 BC Cancer Agency KEL Cancer Info Ctr Available
c.1 BC Cancer Agency VAN Library Available
c.2 BC Cancer Agency VAN Library Available
c.1 BC Cancer Agency VIC Cancer Info Ctr Available
c.2 BC Cancer Agency VIC Cancer Info Ctr Available
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Novel signaling pathways in cancer cells and development of target therapy

https://bccalibrary.andornot.com/en/permalink/catalog21206
Hung, Mien-Chie. [Vancouver, BC?]: BC Cancer Agency. Multi-Media Services , 2013.
Audience
Professional
Call Number
QZ206 B365 2013 v.336
Availability
1 copy, 1 available
More Information
Alternate Title
Monday noon seminar series
BCCA Research Seminar Series
Author
Hung, Mien-Chie
Corporate Author
BC Cancer Research Centre Seminar Series
Place of Publication
[Vancouver, BC?]
Publisher
BC Cancer Agency. Multi-Media Services
Publication Date
2013
Physical Description
60 minutes
Series
BC Cancer Research Centre seminar series 336
Subjects
Neoplasms - drug therapy
Hedgehog Proteins
Transcription Factors
Esophageal Neoplasms
Signal Transduction
Language
English
Material Type
Video
DVD
Audience
Professional
Location
Vancouver Library AV Room
Call Number
QZ206 B365 2013 v.336

Copies

c.1 BC Cancer Agency VAN Library AV Room Available
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Pharmacological considerations with targeted therapy

https://bccalibrary.andornot.com/en/permalink/catalog16241
Sparreboom, Alex. [Vancouver, BC?]: BC Cancer Agency. Multi-Media Services , 2008.
Audience
Professional
Call Number
QZ206 B365 2008 v.244
Availability
1 copy, 1 available
More Information
Alternate Title
Monday noon seminar series
Author
Sparreboom, Alex
Corporate Author
BC Cancer Research Centre Seminar Series
Place of Publication
[Vancouver, BC?]
Publisher
BC Cancer Agency. Multi-Media Services
Publication Date
2008
Physical Description
60 minutes
Series
BC Cancer Research Centre seminar series 244
Subjects
Pharmacokinetics
Antineoplastic Agents - pharmacology
Pharmacogenetics
Language
English
Material Type
Video
DVD
Audience
Professional
Location
Vancouver Library AV Room
Call Number
QZ206 B365 2008 v.244

Copies

c.1 BC Cancer Agency VAN Library AV Room Available
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Role of HIF in cancer : new perspectives

https://bccalibrary.andornot.com/en/permalink/catalog17748
Ohh, Michael. [Vancouver, BC?]: BC Cancer Agency. Multi-Media Services , 2009.
Audience
Professional
Call Number
QZ206 B365 2009 v.261
Availability
1 copy, 1 available
More Information
Alternate Title
Monday noon seminar series
Author
Ohh, Michael
Corporate Author
BC Cancer Research Centre Seminar Series
Place of Publication
[Vancouver, BC?]
Publisher
BC Cancer Agency. Multi-Media Services
Publication Date
2009
Physical Description
60 minutes
Series
BC Cancer Research Centre seminar series 261
Subjects
Hypoxia-Inducible Factor 1
Gene Expression Regulation
von Hippel-Lindau Disease
Genes, Tumor Suppressor
Ubiquitin-Protein Ligase Complexes
Language
English
Material Type
Video
DVD
Audience
Professional
Location
Vancouver Library AV Room
Call Number
QZ206 B365 2009 v.261

Copies

c.1 BC Cancer Agency VAN Library AV Room Available
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Targeting stromal cells for pancreatic cancer therapy

https://bccalibrary.andornot.com/en/permalink/catalog16062
Ng, Sylvia. [Vancouver, BC?]: BC Cancer Agency. Multi-Media Services , 2007.
Audience
Professional
Call Number
QZ206 B365 2007 v.236
Availability
1 copy, 1 available
More Information
Alternate Title
Monday noon seminar series
Author
Ng, Sylvia
Corporate Author
BC Cancer Research Centre Seminar Series
Place of Publication
[Vancouver, BC?]
Publisher
BC Cancer Agency. Multi-Media Services
Publication Date
2007
Physical Description
60 minutes
Series
BC Cancer Research Centre seminar series 236
Subjects
Pancreatic Neoplasms - therapy
Stromal Cells
Language
English
Material Type
Video
DVD
Audience
Professional
Location
Vancouver Library AV Room
Call Number
QZ206 B365 2007 v.236

Copies

c.1 BC Cancer Agency VAN Library AV Room Available
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New approaches to cancer therapy

https://bccalibrary.andornot.com/en/permalink/catalog15764
McCormick, Frank. [Vancouver, BC?]: BC Cancer Agency. Multi-Media Services , 2007.
Audience
Professional
Call Number
QZ206 B365 2007 v.226
Availability
1 copy, 1 available
More Information
Alternate Title
Monday noon seminar series
Author
McCormick, Frank
Corporate Author
BC Cancer Research Centre Seminar Series
Place of Publication
[Vancouver, BC?]
Publisher
BC Cancer Agency. Multi-Media Services
Publication Date
2007
Physical Description
60 minutes
Series
BC Cancer Research Centre seminar series 226
Subjects
Neoplasms - therapy - DVD
Biomedical Research - trends - DVD
Language
English
Material Type
Video
DVD
Audience
Professional
Location
Vancouver Library AV Room
Call Number
QZ206 B365 2007 v.226

Copies

c.1 BC Cancer Agency VAN Library AV Room Available
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New directions : the fight against cancer

https://bccalibrary.andornot.com/en/permalink/catalog15602
Films for the Humanities & Sciences. Princeton, NJ: Films Media Group , 2005.
Audience
Patient or Public
Call Number
QZ201 C215 2005 v.3
Availability
1 copy, 1 available
More Information
Corporate Author
Films for the Humanities & Sciences
Place of Publication
Princeton, NJ
Publisher
Films Media Group
Publication Date
2005
Physical Description
57 minutes
Series
Cancer story
Subjects
Neoplasms - drug therapy - popular works - DVD
Neoplasms - therapy - popular works - DVD
Clinical Trials - popular works - DVD
Drug Approval - popular works - DVD
Language
English
Material Type
Video
DVD
Audience
Patient or Public
Location
Vancouver Library
Call Number
QZ201 C215 2005 v.3

Copies

c.1 BC Cancer Agency VAN Library Available
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Hormones and links to breast cancer treatment

https://bccalibrary.andornot.com/en/permalink/catalog15799
Gelmon, Karen. [Vancouver, BC?]: BC Cancer Agency. Multi-Media Services , 2006.
Audience
Patient or Public
Call Number
WP870 B863 2006 v.3
Availability
3 copies, 3 available
More Information
Author
Gelmon, Karen
Corporate Author
BC Cancer Agency. Breast Tumour Group
Place of Publication
[Vancouver, BC?]
Publisher
BC Cancer Agency. Multi-Media Services
Publication Date
2006
Series
BCCA video telehealth series "Closer to home" 3
Subjects
Breast Neoplasms - therapy
Hormones - therapeutic use
Popular Work
Language
English
Material Type
Video
DVD
Audience
Patient or Public
Location
Vancouver Library
Abbotsford Cancer Info Ctr
Call Number
WP870 B863 2006 v.3

Copies

c.1 BC Cancer Agency ARHCC Cancer Info Ctr Available
c.1 BC Cancer Agency VAN Library Available
c.2 BC Cancer Agency VAN Library Available
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Can targeting the androgen receptor control advanced hormone refractory prostate cancer?

https://bccalibrary.andornot.com/en/permalink/catalog17681
Rennie, Paul S. [Vancouver, BC?]: BC Cancer Agency. Multi-Media Services , 2008.
Audience
Professional
Call Number
QZ206 B365 2008 v.259
Availability
1 copy, 1 available
More Information
Alternate Title
Monday noon seminar series
Author
Rennie, Paul S
Corporate Author
BC Cancer Research Centre Seminar Series
Place of Publication
[Vancouver, BC?]
Publisher
BC Cancer Agency. Multi-Media Services
Publication Date
2008
Physical Description
60 minutes
Series
BC Cancer Research Centre seminar series 259
Subjects
Prostatic Neoplasms - therapy
Receptors, Androgen
Language
English
Material Type
Video
DVD
Audience
Professional
Location
Vancouver Library AV Room
Call Number
QZ206 B365 2008 v.259

Copies

c.1 BC Cancer Agency VAN Library AV Room Available
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Patient's guide to colorectal cancer treatment

https://bccalibrary.andornot.com/en/permalink/catalog15720
Marshall, John L. Manhasset, NY: Oncology Publishing Group , 2005.
Audience
Patient or Public
Call Number
WI520 P298 2005
Availability
7 copies, 7 available
Video Segments:; What is colorectal cancer? (9 minutes); What is chemotherapy? (8 minutes); What you can do (6 minutes); Clinical trials (5 minutes); Patient advice (7 minutes); Interactive video frequently asked questions (10 minutes); Resources and glossary of terms are only downloadable from a c…
More Information
Author
Marshall, John L
Corporate Author
Ryah Creative Group
Place of Publication
Manhasset, NY
Publisher
Oncology Publishing Group
Publication Date
2005
Physical Description
45 minutes
Subjects
Colorectal Neoplasms
Colorectal Neoplasms - therapy
Popular Work
Abstract
Video Segments:
What is colorectal cancer? (9 minutes)
What is chemotherapy? (8 minutes)
What you can do (6 minutes)
Clinical trials (5 minutes)
Patient advice (7 minutes)
Interactive video frequently asked questions (10 minutes)
Resources and glossary of terms are only downloadable from a computer.
Language
English
Material Type
Video
DVD
Audience
Patient or Public
Location
Vancouver Library
Kelowna Cancer Info Ctr
Call Number
WI520 P298 2005

Copies

c.3 BC Cancer Agency ARHCC Cancer Info Ctr Available
c.1 BC Cancer Agency KEL Cancer Info Ctr Available
c.1 BC Cancer Agency VAN Library Available
c.2 BC Cancer Agency VAN Library Available
c.3 BC Cancer Agency VAN Library Available
c.4 BC Cancer Agency VAN Library Available
c.5 BC Cancer Agency VAN Library Available
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Non-small cell lung cancer : new therapies

https://bccalibrary.andornot.com/en/permalink/catalog16157
Information Television Network. Boca Raton, Fla.: Information Television Network, Inc. , 2006.
Audience
Patient or Public
Call Number
WF658 N813i 2006
Availability
2 copies, 2 available
More Information
Corporate Author
Information Television Network
Place of Publication
Boca Raton, Fla.
Publisher
Information Television Network, Inc.
Publication Date
2006
Physical Description
30 minutes
Series
Healthy body, healthy mind 613
Subjects
Carcinoma, Non-Small-Cell Lung - therapy
Lung Neoplasms
Popular Work
Language
English
Material Type
Video
DVD
Audience
Patient or Public
Location
Vancouver Library
Abbotsford Cancer Info Ctr
Call Number
WF658 N813i 2006

Copies

c.1 BC Cancer Agency ARHCC Cancer Info Ctr Available
c.1 BC Cancer Agency VAN Library Available
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Colorectal screening|Treating advanced colorectal cancer : new challenges

https://bccalibrary.andornot.com/en/permalink/catalog16245
Melosky, Barbara, Kennecke, Hagen. [Vancouver, BC?]: BC Cancer Agency. Multi-Media Services , 2006.
Audience
Professional
Call Number
QZ200 B366a 2006 v.1
Availability
2 copies, 2 available
Full conference information obtained from the Annual cancer conference program and abstracts. See ID# 15548. (QZ200 B366 2006); Colorectal screening by Dr. Barbara Melosky (25 minutes); Treating advanced colorectal cancer : new challenges by Dr. Hagen Kennecke (25 minutes)
More Information
Alternate Title
Annual cancer conference
Annual cancer conference : partners in research and care : BC and the world
Author
Melosky, Barbara
Kennecke, Hagen
Corporate Author
BC Cancer Agency. Annual Cancer Conference (2006 November 23-25 : Vancouver, BC)
Place of Publication
[Vancouver, BC?]
Publisher
BC Cancer Agency. Multi-Media Services
Publication Date
2006
Physical Description
50 minutes
Series
BC Cancer Agency annual cancer conference 2006 v.1
Subjects
Colorectal Neoplasms - diagnosis
Mass Screening
Colorectal Neoplasms - therapy
Colorectal Neoplasms - prevention & control
BC Cancer Agency
Abstract
Full conference information obtained from the Annual cancer conference program and abstracts. See ID# 15548. (QZ200 B366 2006)
Colorectal screening by Dr. Barbara Melosky (25 minutes)
Treating advanced colorectal cancer : new challenges by Dr. Hagen Kennecke (25 minutes)
Language
English
Material Type
Video
DVD
Audience
Professional
Location
Vancouver Library AV Room
Victoria Library
Call Number
QZ200 B366a 2006 v.1

Copies

c.1 BC Cancer Agency VAN Library AV Room Available
c.1 BC Cancer Agency VIC Library Available
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20 records – page 1 of 1.