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Health effects of low doses of radiation : perspectives on integrating radiation biology and epidemiology

https://bccalibrary.andornot.com/en/permalink/catalog121020
National Council on Radiation Protection and Measurements. [Bethesda, MD]: National Council on Radiation Protection and Measurements , 2015.
Audience
Professional
Table of Contents:; Cover -- Preface -- Contents -- Executive Summary -- 1. Introduction -- 1.1 Low Doses and Low Dose Rates -- 1.2 Use of Radiation Biology Data to Reduce the Uncertainty in Risk Estimates -- 2. General Approaches to Risk Assessment -- 2.1 Risk Assessment Process and Associated Unc…
More Information
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Corporate Author
National Council on Radiation Protection and Measurements
Place of Publication
[Bethesda, MD]
Publisher
National Council on Radiation Protection and Measurements
Publication Date
2015
Physical Description
1 online resource
Series
Proquest Ebook Central
NCRP commentary 24
Subjects
Radiation Exposure - adverse effects
Radiation, Ionizing
Radiation Dosage
Abstract
Table of Contents:
Cover -- Preface -- Contents -- Executive Summary -- 1. Introduction -- 1.1 Low Doses and Low Dose Rates -- 1.2 Use of Radiation Biology Data to Reduce the Uncertainty in Risk Estimates -- 2. General Approaches to Risk Assessment -- 2.1 Risk Assessment Process and Associated Uncertainties -- 2.2 Modeling Uncertainties: Dosimetric, Epidemiologic and Biological -- 2.3 Transfer of Risk Between Populations of Different Countries -- 2.4 Extrapolating Low-Dose Effects from In Vitro to In Vivo -- Animal to Human -- 3. Studies Integrating Biology and Epidemiology -- 3.1 Epidemiologic Studies Focused on Cancer Outcomes -- 3.1.1 Chromosome Aberration Studies -- 3.1.2 Atomic-Bomb Survivors -- 3.1.3 Pelvic Irradiation Studies -- 3.1.4 Occupational Studies -- 3.1.5 Environmental Background Studies -- 3.1.6 Transgenerational Studies -- 3.1.7 Gene and Radiation Interaction: The Women's Environmental Cancer and Radiation Epidemiology Study -- 3.1.8 Retinoblastoma -- 3.2 Epidemiologic Studies Focused on Noncancer Outcomes -- 4. Bioindicators from Radiation Biology Studies -- 4.1 DNA Damage and Repair -- 4.2 Signaling of DNA Damage at Low Doses -- 4.3 Chromosome Alterations -- 4.4 Mutations -- 4.5 Radiation-Induced Genomic Instability -- 4.6 Modulators of Response -- 4.6.1 Adaptive Responses -- 4.6.2 Bystander Effects -- 4.6.3 Genetic Susceptibility and Interactions with Radiation -- 4.6.4 Interactions with Environmental and Lifestyle Factors -- 5. Closing the Gaps Towards an Integrated Approach -- 5.1 Targeted Research to Identify Adverse Outcome Pathways and Bioindicators of Response -- 5.2 Biologically Based Modeling -- 5.2.1 Biologically Based Dose-Response Approach -- 5.2.2 Systems Biology -- 5.3 Registries of Medical-Imaging Exposures Linked to Outcomes and Biological Materials -- 5.4 Facilities and Interdisciplinary Training -- 5.4.1 Facilities
5.4.2 Interdisciplinary Training -- Abbreviations and Acronyms -- Glossary -- References -- Scientific Committee Members -- NCRP Commentaries
ISBN
9780983545071
Language
English
Material Type
Ebook
Audience
Professional
Location
Internet
Website Notes
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https://login.bccancer.idm.oclc.org/login?url=https://ebookcentral.proquest.com/lib/bccancer-ebooks/detail.action?docID=4394282
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