Author

Sourati, Ainaz

Ameri, Ahmad

Malekzadeh, Mona

Place of Publication

Cham, Switzerland

Publisher

Springer

Publication Date

2017

Physical Description

xvi, 217 p. : ill. ; 24 cm.

Series

EBSCOhost eBook

Subjects

Radiotherapy - adverse effects

Radiation Exposure - adverse effects

Radiation Exposure - prevention & control

Abstract

Table of Contents:

1. Radiation Dermatitis -- 2. Hair Loss -- 3. Radiation Brain Injury -- 4. Radiation Orbital Toxicity -- 5. Ear Toxicity -- 6. Oral Mucositis -- 7. Xerostomia -- 8. Loss of Taste -- 9. Laryngeal Edema -- 10. Radiation Pneumonitis -- 11. Pericarditis -- 12. Esophagitis -- 13. Radiation Gastritis -- 14. Radiation-Induced Liver Disease -- 15. Enteritis -- 16. Radiation Cystitis -- 17. Radiation Proctitis -- 18. Fatigue -- 19. Hematological Side Effects -- 20. Radiation-Induced Nausea and Vomiting (RINV)

ISBN

9783319559490

9783319559506

Language

English

Material Type

Book

Ebook

Audience

Professional

Location

Kelowna Library

Internet

Call Number

WN610 S724 2017

Website Notes

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Copies

Corporate Author

National Council on Radiation Protection and Measurements

Place of Publication

[Bethesda, MD]

Publisher

National Council on Radiation Protection and Measurements

Publication Date

2015

Physical Description

1 online resource

Series

Proquest Ebook Central

NCRP commentary 24

Subjects

Radiation Exposure - adverse effects

Radiation, Ionizing

Radiation Dosage

Abstract

Table of Contents:

Cover -- Preface -- Contents -- Executive Summary -- 1. Introduction -- 1.1 Low Doses and Low Dose Rates -- 1.2 Use of Radiation Biology Data to Reduce the Uncertainty in Risk Estimates -- 2. General Approaches to Risk Assessment -- 2.1 Risk Assessment Process and Associated Uncertainties -- 2.2 Modeling Uncertainties: Dosimetric, Epidemiologic and Biological -- 2.3 Transfer of Risk Between Populations of Different Countries -- 2.4 Extrapolating Low-Dose Effects from In Vitro to In Vivo -- Animal to Human -- 3. Studies Integrating Biology and Epidemiology -- 3.1 Epidemiologic Studies Focused on Cancer Outcomes -- 3.1.1 Chromosome Aberration Studies -- 3.1.2 Atomic-Bomb Survivors -- 3.1.3 Pelvic Irradiation Studies -- 3.1.4 Occupational Studies -- 3.1.5 Environmental Background Studies -- 3.1.6 Transgenerational Studies -- 3.1.7 Gene and Radiation Interaction: The Women's Environmental Cancer and Radiation Epidemiology Study -- 3.1.8 Retinoblastoma -- 3.2 Epidemiologic Studies Focused on Noncancer Outcomes -- 4. Bioindicators from Radiation Biology Studies -- 4.1 DNA Damage and Repair -- 4.2 Signaling of DNA Damage at Low Doses -- 4.3 Chromosome Alterations -- 4.4 Mutations -- 4.5 Radiation-Induced Genomic Instability -- 4.6 Modulators of Response -- 4.6.1 Adaptive Responses -- 4.6.2 Bystander Effects -- 4.6.3 Genetic Susceptibility and Interactions with Radiation -- 4.6.4 Interactions with Environmental and Lifestyle Factors -- 5. Closing the Gaps Towards an Integrated Approach -- 5.1 Targeted Research to Identify Adverse Outcome Pathways and Bioindicators of Response -- 5.2 Biologically Based Modeling -- 5.2.1 Biologically Based Dose-Response Approach -- 5.2.2 Systems Biology -- 5.3 Registries of Medical-Imaging Exposures Linked to Outcomes and Biological Materials -- 5.4 Facilities and Interdisciplinary Training -- 5.4.1 Facilities

5.4.2 Interdisciplinary Training -- Abbreviations and Acronyms -- Glossary -- References -- Scientific Committee Members -- NCRP Commentaries

ISBN

9780983545071

Language

English

Material Type

Ebook

Audience

Professional

Location

Internet

Website Notes

This Proquest title is licensed for ONE BC Cancer staff user at a time. If you are denied access while on a network computer, please try again later.

Authentication via HealthBC sign in required. Use your BC Cancer staff username and ID when prompted.

Corporate Author

National Council on Radiation Protection and Measurements

Place of Publication

[Bethesda, MD]

Publisher

National Council on Radiation Protection and Measurements

Publication Date

2017

Physical Description

1 online resource

Series

Proquest Ebook Central

NCRP report 176

Subjects

Nanoparticles

Radiation Exposure - adverse effects

Radiation Protection - methods

Radiometry

Safety Management - methods

Nanotechnology - standards

United States

Guideline

Abstract

Table of Contents:

1. Executive Summary -- 1.1 Background -- 1.2 Scope -- 1.3 Conclusions and Recommendations -- 1.3.1 General -- 1.3.2 Operational Health Physics -- 1.3.3 Internal Dosimetry -- 1.3.4 Summary -- 2. Introduction -- 2.1 Background -- 2.2 Purpose -- 3. Types and Sources of Nanomaterials Including Radioactive Nanoparticles -- 3.1 Introduction -- 3.2 Naturally Occurring and Incidentally Produced Nanomaterials -- 3.3 Radiation-Induced Synthesis of Nanomaterials -- 3.4 Radioactive Nanomaterials -- 3.4.1 Naturally Occurring Radioactive Nanomaterials -- 3.4.2 Incidentally Produced Radioactive Nanomaterials -- 3.4.3 Radiolabeled Nanomaterials -- 4. Physicochemical Concerns for Exposure to Nanoparticles -- 4.1 Nanoparticle Physicochemical Properties -- 4.1.1 Deposition Within the Respiratory Tract -- 4.1.2 Translocation Across Organ Membranes -- 4.1.3 Surface Area and Reactivity in Biological Systems -- 4.1.4 Particle Shape -- 4.1.5 Particle Agglomeration -- 4.1.6 Material Dispersibility -- 4.1.7 Material Surface Charge -- 4.2 Nanoparticle Exposure Experiences Involving Humans -- 4.2.1 Magic Nano Event -- 4.2.2 Event in China -- 4.2.3 Nickel Sensitization Case -- 4.2.4 Polymer and Metal Fume Experience -- 4.3 Guidance on Managing Physicochemical Concerns for Exposure to Nanoparticles -- 5. Operational Health Physics in a Nanotechnology Environment -- 5.1 Introduction -- 5.1.1 Attention to the Physicochemical Toxicity of Radioactive Nanomaterials -- 5.1.2 Changes that May be Needed for Internal Dosimetry -- 5.1.3 Changes that May be Needed for Dispersion of Airborne Particles -- 5.1.4 Summary of Radiation Program Elements Applicable to Working with Radioactive Nanomaterials -- 5.2 Hierarchy of Exposure Controls for Facility and Process Design -- 5.2.1 Elimination and Substitution -- 5.2.2 Engineered Controls

5.2.3 Administrative Controls -- 5.2.4 Personal Protective Equipment -- 5.3 Use of Radioactive Nanomaterials in Medical Settings -- 5.4 Management and Disposal of Radioactive Nanomaterial Waste -- 5.5 Control of Public Exposure -- 5.6 Emergency Response -- 5.7 Incident Investigation -- 5.8 Effective Risk Communication -- 6. Nanoparticle Issues for Internal Radiation Dosimetry -- 6.1 Framework for Considering Radioactive Nanoparticle Internal Dosimetry -- 6.2 General Approach to Biokinetic Modeling for Intakes of Radioactive Nanoparticles -- 6.3 Radiation Dosimetry of Inhaled Radioactive Nanoparticles -- 6.3.1 Deposition of Inhaled Radioactive Nanoparticles -- 6.3.2 Clearance of Inhaled Radioactive Nanoparticles -- 6.3.3 Respiratory Tract Dosimetry for Radioactive Nanoparticles -- 6.4 Radiation Dosimetry of Ingested Radioactive Nanoparticles -- 6.5 Radiation Dosimetry of Radioactive Nanoparticles for Intact Skin -- 6.6 Radiation Dosimetry of Radioactive Nanoparticles in Wounds -- 6.7 Biokinetics of Nanoparticles that Affect Internal Dosimetry -- 6.7.1 Regional Deposition of Radioactive Nanoparticles -- 6.7.2 Biokinetic Characteristics of Inhaled Radioactive Nanoparticles -- 6.7.3 Biokinetics Example: Monomeric and Polymeric Plutonium -- 7. Dose Assessment and Medical Management for Individuals Exposed to Radioactive Nanoparticles -- 7.1 Approaches for Dose Assessment -- 7.2 Occupational Exposure and Dose Assessment Scenario: Plutonium Processing Facility -- 7.3 Impact of Radioactive Nanoparticles on Dose Assessment -- 7.4 Impact of Radioactive Nanoparticles on Medical Management Decisions -- 8. Conclusions and Recommendations -- 8.1 Hazard and Exposure Assessment -- 8.1.1 Conclusions -- 8.1.2 Recommendations -- 8.2 Operational Health Physics -- 8.2.1 Conclusions -- 8.2.2 Recommendations -- 8.3 Nanoparticle Issues for Radiation Dosimetry

8.3.1 Conclusions -- 8.3.2 Recommendations -- 8.4 Dose Assessment and Medical Management -- 8.4.1 Conclusions -- 8.4.2 Recommendations -- Appendix A. Radiolabeled Nanoparticles -- A.1 Use of Radionuclides to Characterize and Quantitate Nanoparticle Contents -- A.2 Radiolabeled Nanoparticles for Biokinetic and Toxicologic Investigations -- A.3 Radiolabeled Nanoparticles for Diagnostic Medicine -- A.4 Radiolabeled Nanoparticles for Medical Imaging -- A.5 Radiolabeled Nanoparticles for Therapeutic Medicine -- A.6 Use of Radiation-Induced Emissions and Hyperthermal Effects from Nanoparticles in Therapeutic Medicine -- Appendix B. Biokinetic Models -- B.1 Fate of Nanoparticles in the Lungs -- B.2 Particle Clearance and Translocation Pathways -- B.3 Exposure and Biokinetics of Ingested Nanoparticles -- B.4 Human and Animal Studies Using Radioactive Nanoparticles -- Appendix C. Key Concepts for Understanding Nanoparticle Aerosol Properties and Behaviors -- C.1 Introduction -- C.2 A Range of Mechanisms Influence Particle Motion and Collection -- C.3 Behavior of Airborne Nanoparticles is Dominated by Brownian Diffusion -- C.4 Particle Volume Equivalent Diameter, Thermodynamic Diameter, and Aerodynamic Equivalent Diameter are Related -- C.5 Particle Size Distributions are Frequently Lognormal -- C.6 Nanoparticles Dominate the Count Distribution -- C.7 Nanoparticles Exist to Some Extent in the Majority of Occupational Aerosols -- C.8 Smaller Particles have a Greater Fraction of Their Atoms at the Particle Surface -- C.9 Number Concentrations of Concern Depend on the Material of Concern -- C.10 Realistic Airborne Particle Number Concentrations can be Limited by Coagulation -- C.11 Smaller Particles are More Difficult to Dislodge from Surfaces than Larger Particles -- Abbreviations, Acronyms and Symbols -- Glossary -- References -- Scientific Committee and Staff

The NCRP -- Officers -- Members -- Distinguished Emeritus Members -- Lauriston S. Taylor Lectures -- Warren K. Sinclair Keynote Addresses -- Thomas S. Tenforde Topical Lectures -- NCRP Publications -- NCRP Reports -- NCRP Commentaries -- Proceedings of the Annual Meeting -- Lauriston S. Taylor Lectures -- Warren K. Sinclair Keynote Addresses -- Thomas S. Tenforde Topical Lectures -- Symposium Proceedings -- NCRP Statements -- Other Documents

Notes

Title page: March 2, 2017

ISBN

9780913392041

9780913392027

Language

English

Material Type

Ebook

Audience

Professional

Location

Internet

Website Notes

This Proquest title is licensed for ONE BC Cancer staff user at a time. If you are denied access while on a network computer, please try again later.

Authentication via HealthBC sign in required. Use your BC Cancer staff username and ID when prompted.